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Biomedical subjects

L L Kapuller

Publications and source records attributed to L L Kapuller.

At least 55 records · Page 3Linked to original sources

[Treatment of internal hemorrhoids by the method of nonsurgical ligature combined with proctoglivenol].

In the Research Laboratory of Proctology with the clinic of the RSFSR Ministry of Health since 1974 a nonoperative ligature method was employed for treatment of 50 patients at high risk for this affection. A combined use of the nonoperative method and proctoglivenol suppositories is a rather effective therapeutic measure, which is indicated for treatment of hemorrhoids in patients, in whom operative intervention is contraindicated.

Age Factors↗

[Diffuse polyposis of the large intestine as a precancerous condition].

In 86 (49.4%) of 173 patients cancer of the colon of various localizations against the background of diffuse polyposis was diagnosed, rectal involvement being noted in 50%, cancer involvement of the cecum involvement of the cecum and ascending colon--in 5.4% and 7.2% accordingly. These data made it possible to revise an existing concept of preservation of the rectum in radicalsurgery for diffuse polyposis in favour of remaining right portions of the colon.

Adolescent↗

[Morphological features of cancer in chronic non-specific ulcerative colitis].

27 cases of colon carcinoma developing in non-specific ulcerative colitis are studied. High risk of carcinoma diagnosis is shown if the duration of the disease is more than 20 years. The majority of the tumors were moderately differentiated adenocarcinomas originating from zones of growth at the crypt bottoms in the presence of considerable dysplasia.

Colitis, Ulcerative↗

[Small-cell rectal carcinoma coexisted with tubular-villous adenoma].

The paper describes a case of small-cell high-grade endocrine carcinoma of the rectum concurrent with tubular-villous adenoma in a 58 year-old woman. All epithelial cells of adenoma have been ascertained to be "mixed" exoendocrine endocrinocytes (secrete mucus and contain neuroendocrine granules), contain progesterone receptors, and express CK 8, 18, and 19. Some high-grade neuroendocrine carcinoma cells also secrete mucus. The presence of mitotic activity (Ki-67, 35%), high p53 protein expression (more than 50%), marked CK 18 expression, and clinical data confirm high malignancy of this histological type of the tumor.

Adenoma, Villous↗