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Biomedical subjects

L Lidgren

Publications and source records attributed to L Lidgren.

At least 145 records · Page 8Linked to original sources

Biochemical variables related to calcium metabolism in epileptics.

Five biochemical variables, S-Ca, U-Ca, S-P, U-P and S-ALP, all involved in calcium metabolism, have been investigated in 86 epileptics on long-term medication. We found hypocalciuria in half of the epileptics and increased S-ALP in one third. In contrast to earlier reports there was no hypocalcemia, whereas hypercalcemia was found in 7 epileptics. We have previously reported a high frequency of fractures in these epileptics. An increased fracture rate was found in the 13 epileptics with both hypocalciuria and increased S-ALP, indicating osteomalacia.

Aged↗

Incidence of fracture in epileptics.

In 87 epileptics on diphenylhydantoin, the occurrence of non-seizure-related fractures, over a period of 7 years, was six times greater than that found in the normal population. The significant increase in fracture incidence was found to lie within the 45-64 age group indicating that eipleptics are not only more prone to fractures but also have an earlier fracture début.

Adult↗

Prophylactic antibiotics against early and late deep infections after total hip replacements.

A review with a longer observation period is performed of a previously published double-blind investigation of the prophylatic value of cloxacillin against late infections after total hip replacements; In addition, a retrospective patient material is examined. The total material consisted of 1065 total hips. 15.4 per cent deep, late infections were found in the group without prophylaxis and 20 per cent in the one with prophylaxis. The frequency of haematogenous deep infection was estimated to be less than 1 per cent.

Adult↗