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Biomedical subjects

L M Orlova

Publications and source records attributed to L M Orlova.

5 recordsLinked to original sources
PubMed1987

[Ascorbigen and its derivatives--depot preparations of ascorbic acid].

New derivatives of 2-C-/(indolyl-3)methyl/-beta-L-threo-L-glycero-3-hexulofuranosono- 1,4-lactone, vis. 1'-ethylascorbigen, 1'-benzylascorbigen and 1',2'-dimethyl-5'-methoxyascorbigen were obtained. In aquous solutions at physiological temperature and pH values ascorbigens disintegrate rather rapidly to yield L-ascorbic acid, the rate of the latter's formation depending on the substituent in the indole nucleus and increasing with growth of pH and temperature. Intraperitoneal injection of 1'-methylascorbigen to mice leads to steady rise of L-ascorbic acid level in blood plasma.

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PubMedDate not supplied

[Fleas of the eastern Kyzyl Kum and their epizootic significance].

The fauna of fleas in the East Kisil-Kum includes 24 species. Different physicogeographic regions of sands are characterized by different spectra and number of species of fleas. The greatest share in collections is composed by Xenopsylla gerbilli caspica--the parasite of Rhombomys opimus. In autumn the other parasite of this rodent, Coptopsylla lamellifer, is a mass species. All the most significant and long changes in the number of these species are associated with changes in the density of their hosts' population. The most significant in epizootic respect is the flea X. gerbilli caspica from which about 50% of plague agent cultures were isolated.

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PubMedDate not supplied

[Immunochemical study of surface glycoconjugates of yeast-like fungus of the Candida genus].

Two complex preparations (extract I and extract II) of surface antigens were obtained from the yeast-like fungus Candida maltosa by treatment of intact cells with beta-mercaptoethylamine and pronase. Immune diffusion in agar gel revealed antigenic heterogeneity of the preparations. Both of the extracts were found to have at least 3 antigenic components. The extracts induce hypersensitivity of intact guinea pigs and candida sensitization on the 12th day after the injection of Candida maltose intact cells into the animals. The common antigen components of extracts I and II were found by means of immunochemical and chromatographic assays. The extracts preserved the antigenic activity after enzyme hydrolysis with pronase.

Animals↗