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PubMed · 3606674

[Ascorbigen and its derivatives--depot preparations of ascorbic acid].

Iu V Bukin·I L Plikhtiak·V A Draudin-Krylenko·I V Iartseva·L M Orlova
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Abstract

New derivatives of 2-C-/(indolyl-3)methyl/-beta-L-threo-L-glycero-3-hexulofuranosono- 1,4-lactone, vis. 1'-ethylascorbigen, 1'-benzylascorbigen and 1',2'-dimethyl-5'-methoxyascorbigen were obtained. In aquous solutions at physiological temperature and pH values ascorbigens disintegrate rather rapidly to yield L-ascorbic acid, the rate of the latter's formation depending on the substituent in the indole nucleus and increasing with growth of pH and temperature. Intraperitoneal injection of 1'-methylascorbigen to mice leads to steady rise of L-ascorbic acid level in blood plasma.

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AnimalsAscorbic AcidChemical PhenomenaChemistryDelayed-Action PreparationsIndolesKineticsMagnetic Resonance SpectroscopyMiceJournal Article

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Iu V Bukin, I L Plikhtiak, V A Draudin-Krylenko, I V Iartseva, L M Orlova. 1987. [Ascorbigen and its derivatives--depot preparations of ascorbic acid].. https://pubmed.ncbi.nlm.nih.gov/3606674/

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