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Biomedical subjects

L McGlone

Publications and source records attributed to L McGlone.

7 recordsLinked to original sources
PubMed2004

Neonatal genital prolapse.

Genital prolapse is a rare condition in neonates. It is most commonly associated with neural tube defects such as spina bifida. A preterm, growth restricted neonate with genital prolapse without an associated central nervous system anomaly is reported. The risk factors, management and outcome of neonatal genital prolapse are reviewed. The importance of in utero undernutrition as a predisposing factor is emphasized.

Female↗
PubMed2004

Use of magnifying lens to aid neonatal umbilical arterial catheter insertion.

We conducted this trial to test the hypothesis that use of a magnifying lens would facilitate umbilical arterial catheter (UA C) insertion in neonates. Neonates <33 weeks' gestation requiring a UA C were randomized to conventional method of catheter insertion or an experimental method using a 2.0 X magnifying lens mounted on a headband. A total of 44 neonates (Conventional = 23, Experimental = 21) with comparable demographic characteristics completed the study. The time taken for (primary outcome) and rate of successful UAC insertion (secondary outcome) were not significantly different between the two groups (median times: conventional: 88 seconds,experimental: 70 seconds, P = 0. 734) (Success rate: conventional: 19/23 (83%) vs experimental:13/21 (63%), P = 0. 1791 Thus, our hypothesis was rejected.

Catheterization↗
PubMed2003

Congenital arhinia.

Congenital absence of the nose or arhinia is a rare defect of embryogenesis, often associated with other anomalies. It is potentially a life-threatening condition and requires the presence of a highly skilled neonatal resuscitation team at the time of delivery. The associated anomalies often have a significant impact on the immediate as well as long-term outcome of the neonate. Parental counselling is thus vital and a multidisciplinary team approach is required to optimise the neonatal outcome. A neonate with congenital arhinia is reported and the literature reviewed to suggest guidelines for the management of such cases.

Humans↗
PubMedDate not supplied

Virtual elimination of necrotising enterocolitis for 5 years - reasons?

UNLABELLED: A standardised feeding regimen was adopted in 1997 for guiding enteral feeding of neonates <32 weeks' gestation during clinical trials (18 months each) involving erythromycin (n=73) as a prokinetic and carboxymethylcellulose (n=70) as a laxative as well as for during 2 years (n=155) without any trials. Most aspects of the feeding regimen (e.g., milk increments-total volume/day, use of breast milk by choice, etc) were not significantly different from current practices. RESULTS: 298 neonates <32 weeks' gestation (<28 weeks; n=78) were enterally fed during the 5 years. Their demographic characteristics and median (interquartile) age in days at starting (AST) and days to reach full enteral feeds (FFT) of 150 ml/kg/day were not significantly different during these 5 years: [AST: 5 (3-7.5)], [FFT: 4 (3-7)] Only one case of definite NEC (> or =Stage II) occurred during the 5 years. The time to reach full feeds was also reduced by over 54% (including for neonates <28 weeks gestation) compared with a historical cohort. CONCLUSION: Sustained reduction in the time to reach full feeds with virtual elimination of > or =Stage II NEC for 5 years indicates continued benefits of a standardised feeding regimen as a simple preventive strategy to prevent NEC. Whether our specific policy of no enteral feeds in presence of hemodynamic instability associated with PDA requiring indomethacin, and/or sepsis played a role in achieving the significant results needs controlled trials.

Carboxymethylcellulose Sodium↗