Biomedical subjects
Publications and source records attributed to L Montebugnoli.
Transplanted patients could be a source of fear and anxiety for dentist. In the present paper the personal experience on seven patients with transplanted organ undergoing odontoiatric treatment has been referred.
Data from the present clinical research indicate that parental interference during an orthodontic session could influence the cardiovascular system of the dentist.
In the present paper the physical principles of the lever applied on dental extraction have been discussed.
Recent advances in cardio-pulmonary resuscitation during cardiac arrest in odontoiatric center have been exposed.
In the present paper a personal classification and therapeutic strategy about cardiovascular emergency in dentistry has been discussed.
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In the present paper the advantage of muscular flux and resistance determination in the limb over the traditional cardiovascular parameter about operative stress in dentistry has been discussed.
In this study, the effects of epinephrine in the local anesthesia were valued. No significant differences were revealed to cardiovascular response when a group of patients under generic stress were given an anesthetic without epinephrine and a second group of patients underwent an anesthetic with epinephrine. In patients in which epinephrine was injected, a significant fall in diastolic blood pressure was recorded two minutes after the injection and it remained as such for ten minutes. The cardiovascular response during dental extraction has a significant result dissimilar in the two groups of patients. No significant correlation was revealed between the blood pressure and the heart rate in basic conditions and the same parameters during an extraction. There exists a significant correlation between pressure response during generic stress and pressure response during an extraction. These findings suggest that cardiovascular response during dental stress is not in relation with the use of epinephrine with an anesthetic, but rather depends on each individual reaction.
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The relationship between intralymphocytic sodium content (ILSC) and blood pressure (BP) was assessed in a group of 18 untreated patients with essential hypertension. BP was recorded with an automatic device at rest and during mental arithmetic and handgrip. When BP was recorded in the presence of the physician patients with very high ILSC values showed significantly higher values than patients with moderately high ILSC values. This difference was no longer detectable when BP was recorded in a quiet room the patients being alone. ILSC and diastolic BP at rest were significantly related (r=0.80) only when the physician was present. The percent increase in diastolic BP induced by stimulation tests was significantly related to ILSC values (r=0.91). These data suggest that pressor response to adrenergic stimulation in patients with essential hypertension is related to intracellular sodium content.
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1. The sodium concentration in lymphocytes was measured in a group of 66 normotensive subjects (40 without familial hypertension and 26 with familial hypertension), in a group of 81 patients with essential hypertension and in a group of 14 patients with secondary hypertension. 2. The mean value (+/- SD) in normotensive subjects with no history of familial hypertension was 21.9 +/- 3.1 mmol/kg wet weight, which was significantly lower (P less than 0.005) than that of normotensive subjects with familial hypertension (mean value 27.9 +/- 4.2 mmol/kg). Lymphocyte sodium concentration was significantly higher in patients with essential hypertension (33.2 +/- 3.3 mmol/kg; P less than 0.001) than in the subjects with normal blood pressure without familial hypertension. 3. In the patients with essential hypertension there was a significant correlation between lymphocyte sodium concentration and systolic (P less than 0.005), diastolic (P less than 0.001) and mean (P less than 0.001) blood pressure. In the normotensive subjects there was no correlation between the lymphocyte sodium concentration and the blood pressure. 4. The patients with secondary forms of hypertension had normal lymphocyte sodium concentration, except in the case of Conn's disease. 5. Incubation with ouabain increased lymphocyte sodium concentration in the normotensive subjects and patients with essential hypertension; the final sodium concentration was similar in the two groups. 6. When lymphocytes from normotensive subjects without familial hypertension were incubated in plasma of patients with essential hypertension there was an increase in their sodium content.
1. Three groups of young patients with borderline hypertension were studied for a 12 months period. The first was on a free sodium diet while the second was on a low-salt diet. The third group of patients underwent acute salt loading. 2. After 12 months the group on free diet showed a significant increase of intralymphocytic sodium but no change in blood pressure was noted. Five patients who were re-checked after 24 months also had a significant increase in blood pressure. 3. Patients treated with a low-salt diet showed a significant decrease of both intralymphocytic sodium concentration and blood pressure. 4. After acute salt loading, borderline subjects with high intralymphocytic sodium showed a significant greater natriuresis whereas intralymphocytic sodium increased only in those subjects in whom it was initially normal.