The heat regulation of the human body.
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Body Temperature Regulation↗
Biomedical subjects
L Pedersen
Publications and source records attributed to L Pedersen.
Epidemiology and treatment of diabetic ketoacidosis in a community population.
We evaluated the epidemiology of diabetic ketoacidosis in the period 1960-1979. In Frederiksborg County, Denmark, the incidence of ketoacidosis at the county hospital increased from 60 per 100,000 in the period 1943-1963 to 120 per 100,000 in the period 1960-1979. In the investigation period we found an increasing incidence confined to urban areas. Precipitating factors were not somatic in 53% of the cases. Patients in the lowest social class (V) were in a higher risk group, experiencing ketoacidosis more often and having a higher frequency of severe acidosis. Forty-nine percent of the patients have had a diabetes duration of more than 5 yr. The lethality rate decreased from the period 1943-1963 and was 4.7% in the investigation period 1960-1979.
Adolescent↗
Combined treatment of advanced malignant melanoma with coumarin and cimetidine.
An immunostimulant therapy with coumarin and cimetidine was evaluated in 17 patients with advanced malignant melanoma. Induction therapy with coumarin 100 mg daily was given for 8 weeks, after which cimetidine 1000 mg daily was added. No patients had been previously treated with cytotoxic drugs. All patients had good performance status. Sixteen patients experienced progressive disease, and only one patient showed no change lasting for 30 weeks. It is concluded that treatment with this schedule of coumarin and cimetidine is without effect in advanced malignant melanoma.
Adult↗