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Biomedical subjects

L Plavoşin

Publications and source records attributed to L Plavoşin.

29 records · Page 2Linked to original sources
PubMedDate not supplied

Ultrastructural aspects of herpetoviruses.

Thin-section electron microscopy of several herpetovirus strains recovered in the laboratory from human hosts and rodents visualized typical spherical particles when the strains were propagated in vitro at a temperature corresponding to the body temperature of their natural host. In contrast, viral growth at a suboptimal temperature often resulted in aberrant viral structures.

Animals↗
PubMedDate not supplied

The role of vaccinia virus in the evolution of some human hemopathies.

Six cases of severe hemopathy, detected following smallpox revaccination are described. Their onset was favoured by vaccinia virus-induced suppression of cell-mediated and humoral immunity. In two leukemia patients humoral immunity was present, but insufficient to assure protection of the diseased organisms, the outcome being fatal. The pancytopenia syndrome recorded in 4 patients with anergy caused by autoimmune mechanisms had different outcomes: favourable in 2 cases and fatal in the other 2 patients, who died within 4 years.

Hematologic Diseases↗
PubMedDate not supplied

[Direct relation between the significantly increased IgG specific antibody titer and the clinico-evolutive form in respiratory infections in infants and children. IgA and IgD levels in the evolution].

Of 69 children suffering from acute respiratory infections, with increased IgG titers 34 presented normal or high IgAs titers in the laryngotracheal exudate. All these patients had a favourable evolution. The other children with low IgAs levels or absent IgAs in the laryngotracheal exudate had a prolonged relapsing evolution, regardless of serum IgG levels. The presence of IgA 7S in the laryngotracheal exudate did not influence the course of the disease. As a conspicuous parallelism was observed between laryngotracheal exudate IgAs and serum IgA it was assumed that IgAs participates in the formation of serum IgA "mixtures". Increased IgD values were found in 34 of these patients, ten of whom presented respiratory allergy and recurrent infections.

Adolescent↗
PubMedDate not supplied

[The epidemiological aspects of cytomegalic infection in the Banat region, Romania].

A survey was conducted on 711 patients, adults and children. The results indicated the high incidence of cytomegalovirus infection among population and confirmed the virus transmission through blood transfusion. The existence of congenital infection in newborn seems to be confirmed. Some prevention measures are suggested.

Adolescent↗
PubMedDate not supplied

The influence of modifications in the potency of smallpox vaccines on the immunological reactivity of the organism.

The possible influence of shipment and storage conditions upon the potency of smallpox vaccines was investigated by testing the direct effect of vaccine potency on the type of cutaneous reaction and on the level of serum antibodies. Vaccine no. 1--freshly prepared, shipped and stored at +4 degrees C--proved to be more potent than vaccine no. 2, at the limit of its efficiency, shipped and maintained under usual conditions. To maintain the initial potency of smallpox vaccines it is recommended either to improve the shipment and storage conditions, or to use a lyophilized vaccine.

Adult↗
PubMedDate not supplied

Comparative study of cutaneous scars and HAI antibodies after smallpox revaccination.

The number and aspect of cutaneous scars and the HAI antibody titer were recorded in 154 20-21-year-old subjects before smallpox revaccination, 30 and 300 days afterwards. In 38.3% of the vaccinees there were no postvaccinal scars 300 days after revaccination, but the absence of residual scars did not necessarily indicate a failure of immunization, since the increase in mean HAI antibody titer was significant in most of the cases.

Adult↗