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Biomedical subjects

L Raymond

Publications and source records attributed to L Raymond.

121 records · Page 7Linked to original sources
PubMed1975

[Creation of an intercantonal tumor register].

A population-based Cancer Registry is a permanent system which records all the malignant tumors occurring in a particular geographical area. Its main objective is to set up the basis for the establishment of statistics, either for practical use (cancer control) or for research. More than a hundred such registries exist nowadays throughout the world, and in Switzerland a number have been recently created or are in process of organization (cantons of Geneva, Neuchâtel, Vaud, Zurich, Basel). A coordination group has accordingly been created to harmonize the data and the coding system, in order to allow the organization of an Intercantonal Registry.

Neoplasms↗
PubMed1972

Possible mechanism for the antiarrhythmic effect of helium in anesthetized dogs.

Breathing a mixture of 75 percent helium and 25 percent oxygen instead of 75 percent nitrogen and 25 percent oxygen reduced the occurrence of dangerous cardiac arrhythmias after ligation of the circumflex coronary artery in open-chest dogs anesthetized with pentobarbital. In dogs not subjected to circumflex ligation, the sensitivity of blood pressure, heart rate, and extrasystoles to epinephrine injected intravenously was not altered by the substitution of helium for nitrogen; however, helium did reduce the baseline heart rate and the concentration of endogenous plasma catecholamines. The antiarrhythmic effect of helium may thus be mediated by changes in sympathetic activity.

Anesthesia, General↗
PubMedDate not supplied

[Mortality of a group of psychiatric patients under ambulatory care in Geneva].

It is known from former studies that psychiatric patients have a mortality rate higher than that of the general population. This cannot be explained by causes of death that may be specific of psychiatric illness (as suicide for example). The objective of our project is to find if there is such an over mortality in our population, to evaluate to what factors it is related and specially what are the causes of death.

Ambulatory Care↗
PubMedDate not supplied

[Diet and cancer of the pancreas].

A case-control study was carried out in Geneva on the basis of an interview involving 88 new cases of pancreatic cancer and 336 controls. The percentage of histologically confirmed cases was 67 p. 100. Controls were drawn at random from the general population. An excess risk was observed with increased consumption of fatty foods. This excess, however, was only significant for butter; in contrast, margarine was associated with a reduction in risk (relative risk = 0.35, p less than 0.05). Meat intake did not modify the risk, except for lean pork, for which the risk was significantly reduced. For carbohydrates, an excess risk was observed, with a dose-response effect. Fresh fruit and vegetables led to a marked and significant reduction in risk. Among beverages, beer was the only one for which consumption entailed an increased risk (RR = 2.85, p less than 0.05). The results concerning tea and coffee were not significant, but there appeared to be a trend towards an increase in relative risk.

Adult↗
PubMedDate not supplied

[Analysis of the antigenic structure of influenza A/USSR/90/77 virus hemagglutinin].

Evolution of the antigenic structure of influenza virus hemagglutinin with the antigenic formula HA1 was studied by the determination of the capacity for interaction with monoclonal antibody and aminoacid substitutions in the protein. Consecutive changes in protein epitopes were found in isolates accumulating from the time of isolation of H1 influenza viruses in 1977.

Amino Acid Sequence↗