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Biomedical subjects

L Raymond

Publications and source records attributed to L Raymond.

At least 109 records · Page 6Linked to original sources

[High-density lipoproteins in children with coronary diseases].

Low HDL-cholesterol and increased LDL-cholesterol have been shown to be cardiovascular risk factors. Recently, HDL/serum cholesterol and HDL/ LDL-cholesterol ratios have been advocated as more reliable indices of cardiovascular risk factors. In a comparative study, lipoprotein-cholesterol and lipoproteins-triglycerides as well as the HDL/serum cholesterol and HDL/LDL-cholesterol ratios were determined in children of patients with coronary heart disease (CHD) and in healthy control children. Sons of CHD patients had significantly lower HDL-cholesterol and HDL/LDL-cholesterol ratios than controls. In daughters, the HDL-cholesterol and HDL/LDL ratio were also decreased reaching significance in HDL only in the 12 to 16 year age group. Under comparative environmental situations, the results suggest that low HDL-cholesterol in children of CHD patients could be genetically determined.

Adolescent↗

[Towards the development of a global index of functional disability based on the O.E.C.D. questionnaire. Items in a Swiss survey (author's transl)].

This study is based on a sample of 1500 persons, representative of the general population aged 65 years and over in Geneva and the central Valais region. The questions used to evaluate the level of disability are those selected by the OECD working group. They were included in a self-administered questionnaire. A global score of disability is created by using both an endogenous and an exogenous approach. The endogenous approach attempts to isolate a limited number of factors (factorial analysis) and to order the disability items (Guttman Scale). The exogenous approach adopts as criteria a global assessment of the health of each individual. The discussion of different systems of scoring is based on the distribution of different scores and their intercorrelations.

Activities of Daily Living↗

[Alcohol, tobacco and food consumption in pancreatic diseases. Preliminary results of a study of 1000 cases].

The incidence of the cancer of the pancreas is particulary high in Geneva. To determine the possible effects of tobacco, alcohol and/or food, the consumption habits of patients with digestive diseases have been studied at the University Hospital of Geneva since 1977. The present contribution deals with pancreatic patients only. These patients' consumption of tobacco, alcohol and food has been compared with that of standardized controls randomly selected from the Geneva population. A relationship between pancreatic cancer and lifetime tobacco consumption was found on the one hand, and on the other a relationship between chronic pancreatitis and lifetime alcohol consumption.

Alcohol Drinking↗

[Alcohol, tobacco and food consumption in liver cancer and cirrhosis. Preliminary results].

In German the consumption of food among cirrhotic patients, whether male or female and among male patients with primary liver cancer (PLC), is virtually the same as in normals. Alcohol consumption is very high in all three groups. The heaviest drinkers are the cirrhotic males, but the highest patient/control ratio is found among cirrhotic females (X 5.4). Total alcohol ingestion during life appears to be higher in patients with PLC plus cirrhosis than in those with PLC without cirrhosis. Tobacco consumption by male cirrhotic and PLC patients is the same as in controls. Conversely, cirrhotic females smoke seven times as much as their standardized controls.

Alcohol Drinking↗

Decreased HDL cholesterol in prepubertal and pubertal children of CHD patients.

Prepubertal boys and pubertal girls and boys selected because of the occurrence of acute myocardial infarction in their father or mother were characterized by a low HDL cholesterol when compared to healthy controls. This observation extends our previous observations of low HDL cholesterol in adult relatives of CHD patients to the children of the same patients. The occurrence of an HDL abnormality in young children demonstrates that the low HDL cholesterol precedes the occurrence of cardiovascular disease. Low HDL cholesterol was associated with increased VLDL cholesterol in prepubertal children and pubertal boys without significant increase in VLDL triglycerides. Smoking and drinking habits, and physical activity which are environmental factors known to affect HDL did not differ between these children and the controls and cannot account for the observed differences. The results show that the low HDL cholesterol is detectable early in life in close relatives of CHD patients, persists throughout the lifespan and is possibly genetically determined.

Adolescent↗

[Maturation of the cervix by prostaglandins before inducing termination of pregnancy, in the first trimester (author's transl)].

A new technique for instilling the gel of PGF2 alpha into the endocervix is presented. The study is concerned with 100 therapeutic terminations of pregnancy by dilatation and suction carried out in the first trimester of pregnancy. The efficacy of PGF2 alpha gel is compared with that for tablets of PGE2 and a placebo group. Softening of the cervix was evaluated using a tocodynamometer. PFG2 alpha gel often gives remarkable results, but the response to treatment is unpredictable. Secondary effects, and in particular digestive effects, occur frequently but are always easily controlled.

Abortion, Induced↗

[Geographic distribution in some latin countries of cancers of the alimentary tract (author's transl)].

Geographic distribution in some latin countries of cancers of the alimentary tract. A comparison of alimentary tract cancer incidence rates has been undertaken from the results of 5 latin cancer registries. The most striking features are the high incidence rates for gastric cancers in the provinces of Zaragoza and Piemont, for colorectal cancers in the canton of Geneva, and in the countries of Côte-d'Or and Bas-Rhin. Tumour localization in the large bowel differs significantly between Geneva and the French counties. The canton of Geneva has the highest rate for cancer of the pancreas, French countries for cancer of the oesophagus in males. Sex ratio for primary cancer of the liver differs considerably from one region to another.

Digestive System Neoplasms↗