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Biomedical subjects

L Romics

Publications and source records attributed to L Romics.

At least 109 records · Page 6Linked to original sources

Abnormal fat metabolism in chronic renal failure.

The serum triglyceride and cholesterol levels, the cholesterol and triglyceride concentrations in the lipoprotein fractions, as also postheparin lipoprotein-lipase activity (PHLA) were determined in 18 haemodialysis-patients with chronic renal failure. Hypertriglyceridaemia and hypocholesterolaemia were found together with increased VLDL- and LDL + HDL-triglyceride and decreased HDL-cholesterol concentrations. At 10 min after administration of heparin, enzyme activity was normal, at 20 min it was abnormally decreased.

Adult↗

Early retinal vascular signs in hyperlipoproteinaemia.

A total of 23 hyperlipoproteinaemic patients between 24 and 46 years of age were subjected to fluorescein retinography. Early microangiopathy was demonstrated in 12 cases. In 3 of these, the oral glucose tolerance test was normal and the family history of diabetes was negative. It is suggested that hyperlipoproteinaemia, mainly hypertriglyceridaemia, constitutes one of the factors accounting for the microangiopathy. The frequency of angiopathy was particularly high in the group marked by a family history of diabetes with a normal glucose tolerance test.

Adult↗

Serum lipids and lipoproteins in chronic liver disease.

Serum cholesterol, triglyceride, total lipids and the lipoprotein pattern were studied in 169 cases chronic liver disease confirmed by biopsy. On the ground of the immunological and morphological results the patients were classified into five groups. In chronic persistent hepatitis no significant abnormality was found. In chronic aggressive hepatitis and in cirrhosis of the liver the serum cholesterol level was significantly reduced. In fatty infiltration of the liver the serum cholesterol, triglyceride and total lipid concentrations were significantly increased, as compared with the normal values and with the figures obtained in the cases of chronic inflammatory liver disease. In the cases of cirrhosis with additional diabetes the lipid values were likewise increased. In chronic aggressive hepatitis and in cirrhosis of the liver the levels of pre-beta and alpha lipoprotein were decreased, in fatty infiltration of the liver those of beta and pre-beta lipoprotein were increased.

Adolescent↗

Carbohydrate metabolism in various types of hyperlipoproteinaemia.

Insulin secretion has been studied after an oral glucose load in 81 patients with primary hyperlipoproteinaemia and 15 control sugjects. Glucose tolerance was reduced mainly in Type IV, and to a lesser extent in Type IIB hyperlipoproteinaemia. Insulin secretory response to glucose was reduced in Type V and heterogeneous in Type IV hyperlipoproteinaemia. No correlation was found between the triglyceride level and the rate of insulin secretion.

Blood Glucose↗

Effect of methandrostenolone on serum triglyceride and cholesterol levels in diabetic patients.

Eighteen adult diabetic patients were treated with methandrostenolone in daily doses of 15 mg for 3 weeks. Serum triglyceride and cholesterol levels and lipoprotein lipase activity were determined before and after treatment. In patients with intense hypertriglyceridaemia, triglyceride concentration decreased and, with the exception of a single patient, lipoprotein lipase activity returned to normal. Cholesterol concentration did not change characteristically.

Blood Glucose↗