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Biomedical subjects

L Solaro

Publications and source records attributed to L Solaro.

8 recordsLinked to original sources

Vancomycin and ceftazidime in the treatment of CAPD peritonitis.

102 episodes of continuous ambulatory peritoneal dialysis (CAPD) peritonitis were studied prospectively during a 288-day period at The Queen Elizabeth Hospital, Birmingham. Organisms were isolated from 76% of the episodes, with coagulase-negative staphylococci, being the most commonly encountered organism (55%). Initial treatment consisted of intraperitoneal vancomycin and ceftazidime with subsequent adjustment on the basis of antibiotic sensitivities. With this regimen, 83% of the positive cultures became negative by 72 h, 9.8% of cases relapsed and removal of the CAPD catheter was necessary in 8 patients (7.8%). Overall, 92% of cases were cured. No adverse drug reactions were seen. This combination of antibiotics appears effective and safe in the treatment of CAPD peritonitis.

Adolescent

Post-transplant peritonitis in patients undergoing continuous ambulatory peritoneal dialysis.

Two patients previously managed by continuous ambulatory peritoneal dialysis for end stage renal failure received cadaveric renal transplants. The peritoneal catheter was capped off and left in situ postoperatively. Both patients developed bacterial peritonitis shortly after transplantation. It was felt that the infections were associated with the presence of the indwelling peritoneal catheter as there was no clinical evidence of peritonitis at the time of transplantation.

Aeromonas

[Infectious complications of continuous ambulatory peritoneal dialysis].

Continuous ambulatory peritoneal dialysis (CAPD) is of proven value in the treatment of many patients with chronic renal failure. Infective peritonitis remains the major complication of this form of therapy and repeated infections may result in catheter removal and conversion to haemodialysis. The most appropriate antibiotic treatment, the duration and route of administration are still areas of investigation. The aim of this paper is to discuss the diagnosis, management and prevention of peritonitis in CAPD.

Humans

Fastidious bacteriuria and pyuria.

Mid stream specimens of urine that showed pyuria or bacteriuria on direct microscopy and no bacterial growth on initial routine culture were collected from 346 patients. These specimens were cultured for the presence of fastidious organisms using two different test systems. One system used non selective media and the other used selective media. Any fastidious organism isolated was identified by standard methods. Lactobacilli were the only fastidious organisms isolated in significant numbers. Using comparable test systems, equivalent numbers of Lactobacilli were isolated from both test and control group and because of the difficulty in specimen collection, these are to be considered as possible contaminants.

Adult