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Biomedical subjects

L V Nazarchuk

Publications and source records attributed to L V Nazarchuk.

At least 19 recordsLinked to original sources
PubMed2001

[Homeostasis indexes of staphylococcal anatoxin immunized blood donors, previously immunized with tetanus toxoid].

On the 50 volunteers from 20 to 40 years old gomeostasis indexes of inoculating by staphylococci cleaning adsorbing anatoxini donors, before have been revactinated against tetanus, were studied. It was established, that attract of plasmaferes donors to consistent immunization by tetani and staphylococci anatoxini don't call negative alterations in their gomeostasis indexes. Results of study demonstrate, that it's possibly to attract for immunization by staphylococci anatoxini donors, before have been revactinated against tetanus.

Adult↗
PubMed2001

[The protective effect of anti-Pseudomonas blood preparations].

Human blood antipseudomonas preparation activity has been studied on the model of Ps. Aeruginosa etiology sepsis in white not pedigree mice. It has been found out that antipseudomonas plasma and antipseudomonas immunoglobulin with antibody tire 1:80 possess marked therapeutic properties. The obtained results of the experimental studies are the grounds for clinical studies carrying out with the use of blood antipseudomonas preparations in combined therapy of the patients with diseases of Ps. Aeruginosa etiology.

Animals↗
PubMed1999

[The effect of food products with an elevated radionuclide level on the blood and urine indices in rats].

Food influence, including raw meat with radionuclides (6.66 x 10(3) - 20.72 x 10(3) Bq/kg) during 30 days, on some homeostasis values was studied in white not pedigree rats. Erythrocyte number decrease, leukocyte total number increase by twice, young cell-metamyelocyte appearance, the decrease of total protein quantity and of blood serum gamma-globulin fraction level, liver enzyme activity decrease, and liver function disturbance have been ascertained. The obtained data can be the grounds for the future studies in the field of prognostic criterion development for the evaluation of ionizing irradiation small dose effect on the organism.

Animals↗
PubMed1999

[The protective activity of anti-Proteus blood preparations].

Human blood anti-Proteus preparation activity has been studied on the model of Proteus etiology sepsis in white not pedigree mice. It has been found out that anti-Proteus plasma and anti-Proteus immunoglobulin with antibody titre 1:80 possess marked therapeutic properties. The obtained results of the experimental studies are the grounds for clinical studies carrying out with the use of blood anti-Proteus preparations in combined therapy of the patients with diseases of Proteus etiology.

Animals↗
PubMed1998

[Natural antileptospirosis immunity in donor-capable subjects].

Natural antileptospirosis immunity of blood giving capable population of Kyïv was studied in 853 persons. It has been ascertained that during a year natural antileptospirosis antibodies can be found out in blood serum of people with different by ABO system blood groups. Antileptospirosis antibodies of high titres (> 1:80) are mostly present in spring and autumn.

ABO Blood-Group System↗
PubMed1997

[The antidiphtheria immunity of the eligible donor population].

Antidiphtheritic antibodies were studied in the blood serum of Kiev and Kiev region population capable of blood donation (984 persons). It has been found out that antidiphtheritic antibodies were present in men's and women's blood serum of different blood groups (by ABO system) during a year. Antidiphtheritic antibodies with high titers > 1.80 were most often found in autumn, winter and spring in people having A (II), B (III) and AB (IV) blood groups.

ABO Blood-Group System↗
PubMed1992

[The antibacterial immunity of people under dynamic observation in an altered radiation situation].

The comparative study of the isolation rate, level, antigenic and class specificity of serum antibodies to the causative agents of purulent septic infections (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus mirabilis) and acute enteric infections in healthy adults with different ABO blood groups before (836 persons) and after (1,429 persons) the catastrophe at the Chernobyl nuclear power station was made. The study revealed the fact that the genesis of antibodies directed against different microorganisms can be stimulated without additional antigenic challenge in the form of disease or immunization, which was definitely indicative of the influence of small radiation doses in Kiev on the humoral immunity of the population. The multifactor character of the dependence of antibacterial antibody formation under altered radiation conditions on the specific features of the infective agent and the intensity of its circulation among the population, individual immune responsiveness of the body and concrete radiation conditions was established.

Accidents↗
PubMed1991

[Advisability of using donor blood immunoglobulin preparations for treating infections caused by Pseudomonas aeruginosa].

Resulting from the studies of 623 series of the donor blood immunoglobulins, it was established that 19.2% of the series of a commercial preparation put on the market by the Republican blood service contain the natural antibodies to O-antigen and antigens of the Pseudomonas aeruginosa extracellular mucus at the titer of 1:80 and more. Series of the immunoglobulin preparation with a high content of specific antibodies can be used for the treatment of purulent-septic complications caused by Pseudomonas aeruginosa.

Animals↗
PubMed1991

[Dynamic anti-Proteus immunity in plasma donors during plasmapheresis].

A study is presented of homeostasis in 18 volunteer donors after immunisation with Proteus vaccine and in the dynamics of subsequent plasmapheresis for 12 months. It was shown that as a result of anti-Proteus immunisation there occurs an increase of the titer of anti-Proteus antibodies in the blood serum which was maintained at a high level in the course of plasmapheresis for three months. Indices of the peripheral blood, urine, liver function, humoral unspecific and cellular immunity were within normal levels. The blood of donors immunized with Proteus vaccine is a source of obtaining anti-Proteus plasma--an immune allogenous preparation for complex treatment of patients with severe forms of diseases of Proteus etiology.

Adult↗