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Biomedical subjects

L V Nazarchuk

Publications and source records attributed to L V Nazarchuk.

At least 37 records · Page 2Linked to original sources

[Immune response of donors, previously hyperimmunized with staphylococcus anatoxin to Pseudomonas aeruginosa antigen].

The authors studied the immune response of the body of 23 donors formerly hyperimmunized with staphylococcal anatoxin to pyocyaneus antigen. It was established that immunization of these donors with Bacillus pyocyaneus anatoxin did not produce pathological reactions of the body, resulted in activation of the immune systems and production and antipyocyaneus antibodies.

Antibody Formation↗

[Immune response of donors during immunization with staphylococcus anatoxin].

The content of antistaphylococcal antitoxins--antialphastaphylolysins was examined in the blood serum of three groups of blood donor volunteers. It is shown that volunteer blood donors immunized according to two schemes with prophylactic purposes may be a source of antistaphylococcal plasma. Additionally antistaphylococcal plasma may be obtained from non-immune donors showing high titers of antialphastaphylolysins revealed by the screening method.

Antibody Formation↗

[Specific immunity in patients with severe burns complicated by Pseudomonas infection].

The authors have studied 500 samples of blood serum in 262 patients at the age of from 17 to 70 years with thermal burns of different severity degree, depth of injury and location, which were followed by severe infective processes of pyocyanic etiology, and also in reconvalescents of the burn disease. It was established that despite the high degree of staphylococcal and pyocyanic sensibilization, the specific immune response against the background of infective process developed only in a small number of patients with severe burns.

Adult↗

[Antileptospiral antibodies in the blood serum of donors].

The authors investigated the content of antileptospiral antibodies in 930 blood sera of nonimmunized blood donors. It was established that high titers of antileptospiral antibodies are contained in 5.2% of practically healthy persons.

ABO Blood-Group System↗

[Serological diagnosis and immunological aspects of Proteus infection. V. Design and trial of polyvalent antigenic preparations].

The main principles of the development of Proteus polyvalent antigen and erythrocyte diagnosticum, including the selection of the initial strains according to the clinical importance of their H-antigens and to the variety of their partial factors, the combination of monoantigens to form a polyvalent antigenic preparation with due regard to the potency of each component and the use of the preparation in serological tests in accordance with its summary potency, as well as the simultaneous loading of formaldehyde-fixed and tannin- or bisdiazo benzidine-treated sheep red blood cells with sensitins, have been worked out. The diagnostic value of these preparations has been confirmed by the study of serum samples from 579 patients with intestinal and urological infections (among them 153 patients releasing Proteus) and 245 healthy persons.

Adult↗

[Experimental substantiation of the possibility to obtain anti-Proteus plasma].

The possibility to produce the anti-Proteus plasma is experimentally substantiated. It is determined that polyvalent Proteus antigen immunization permits producing blood immune preparation, that is the high-active anti-Proteus plasma. its antibodies belonging to the class of immunoglobulin G. The anti-Proteus plasma in liquid (at t = 6 degrees divided by 2 degrees C) and in frozen (at t = 20 degrees-5 degrees C) forms retains the specific activity for 3 days and 6 months, respectively.

Animals↗