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Biomedical subjects

L V Nazarchuk

Publications and source records attributed to L V Nazarchuk.

49 records · Page 3Linked to original sources
PubMedDate not supplied

[The natural anti-Pseudomonas aeruginosa and anti-Proteus immunity of the suitable donor population].

The natural anti-pyocyanic and anti-Proteus immunity of donorable population of Kiev before the accident at Chernobyl Atomic Power Plant has been studied. Blood serums of 3024 deliberately non-immunized persons have been studied. It is determined that there are natural anti-pyocyanic and anti-Proteus antibodies in blood serum of people with different group belonging during the all periods of a year (by ABO system). The anti-pyocyanic and anti-Proteus antibodies of high titers in blood serum are found in summer most frequently.

ABO Blood-Group System↗
PubMedDate not supplied

[Experimental study of polyvalent proteus antigen immunogenicity].

The experiments on 52 rabbits have been carried out to show the possibility to use Proteus antigen with high content of H-component (H1; H2; H3 Proteus antigens are most frequently found) for active immunization to make highly specific humoral immunity. The optimal scheme of immunization consists of 3 subcutaneous injections in doses of 0.25-0.25-0.5 mg of antigen within 7 days intervals and 0.25 mg dose of single revaccination. The duration of cycle immunization is 14 days.

Animals↗
PubMedDate not supplied

[Natural antistaphylococcal immunity in a potential donor population].

Blood serums of 1842 donorable Kiev inhabitants have been examined. It is shown that blood serum of people with different group belonging (by the ABO system) contains natural antialphastaphylolysins during the whole year. High titres of antialphastaphylolysins (3.0.10(3) ME/1-5.0.10(3) ME/1) are most frequently revealed among the persons of donorable age with group belonging A (II) in summer and spring.

ABO Blood-Group System↗
PubMedDate not supplied

[Obtaining anti-tetanus immunoglobulin from blood plasma of immunized dogs].

Dogs were immunized by tetanic anatoxin. Eight series of antitetanic immunoglobulin with the antitoxin activity from 100.10(3) IU/l to 700.10(3) IU/l were produced from blood plasma. That immunoglobulin was used to study passive and active-passive immunization for tetanus prophylaxis and treatment in the strictly allogenic system.

Animals↗
PubMedDate not supplied

[The dynamics of the level of antiprotein antibodies in the recipient blood serum under different conditions of the passive inoculation of rabbits with allogeneic antiprotein blood preparations].

Dynamics of the content of antiproteic antibodies in the recipient blood serum was studied during intravenous and intramuscular passive immunization with allogenic antiproteic blood preparations. Experiments were carried out on 98 Chinchilla rabbits. Doses of the injected preparation, specific antibodies titres and the number of injections were varied. The schemes of application of antiproteic plasma and antiproteic immunoglobulin are presented.

Animals↗
PubMedDate not supplied

[The criteria for forming risk groups among the population exposed to ionizing radiation after the accident at the Chernobyl Atomic Electric Power Station].

Studied were particular features of peripheral blood, certain immunological and biochemical indices under long-term exposure of human body to radiation after the accident at the Chernobyl Nuclear Power Plant. The study comprised 5578 individuals. The examinees were liquidators of the Chernobyl accident sequels (n = 1052), inhabitants of Pripyat evacuated from the town (n = 850), the Kiev SSBT primary donors (n = 1738). Control group consisted of 936 Kievans who had been examined before the accident between 1982-1985 by the same methods. The results obtained allowed for the most informative indices to be found in order that risk groups might be formed.

Air Pollution, Radioactive↗
PubMedDate not supplied

[Homeostatic indices in persons subjected to ionizing radiation exposure].

Over the period of 1986-1990 a comprehensive evaluation was carried out in a series of a 5578 subjects exposed to ionizing radiation because of Chernobyl NPP breakdown, using hematologic, immunologic and biochemical methods of investigation. The above series included liquidators of aftermath of the accident, residents of Pripyat' and Kiev. Changes were revealed in all the parameters studied. In view of the abnormal changes in the values for blood, immunologic status and biochemical tests characterizing the functional state of the liver in those subjects having been in the area of abnormal radiation, as well as its potential remote sequelae, it is advisable that the above contingents of the population be under prophylactic management.

Air Pollution, Radioactive↗