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Biomedical subjects

L Wiśniewski

Publications and source records attributed to L Wiśniewski.

At least 19 recordsLinked to original sources
PubMed1985

A new case of partial trisomy of 17 long arm. Densitometric analysis of aberrations.

Partial trisomy of the long arm of the chromosome 17 was found in a male infant with severe psychomotor retardation and numerous developmental anomalies. Differential staining with GTG, QFQ and CBG methods revealed an excess of genetic material on the short arm of chromosome 14, which was preliminarily identified as the distal part of chromosome 17q. Using an automatic picture analyser, chromosome break points were found in the 17q12 and 14p12 bands. The patient's karyotype was identified as 46,XY,t(14;17) (14qter----14p12:17q12----17qter).

Abnormalities, Multiple↗
PubMed1981

Culture conditions modify the effects exerted by human fetal alpha-fetoprotein (AFP) on some lymphocyte functions in vitro.

Incorporation of (methyl-3H)-thymidine to DNA of allogeneically and phytohaemagglutinin (PHA)-stimulated lymphocytes cultured in the presence of various concentrations of AFP from human blood cord serum was investigated. The cells were kept in Parker medium supplemented with autologous plasma, calf serum or human AB serum. AFP in concentrations of 5-75 micrograms per one millilitre of culture caused various degrees of inhibiton of responding lymphocyte proliferation. These effects were dependent on the composition of the culture medium, type of lymphocyte stimulation and their individual properties.

Adult↗
PubMed1980

Culture medium components modify the effects exerted by alpha-fetoprotein (AFP) on lymphocyte response.

Incorporation of [methyl-3H]thymidine to DNA of lymphocytes cultured in the presence of various concentrations of alpha-fetoprotein (AFP) from human cord blood serum was investigated. It was found that AFP by itself does not exert mitogenic effects. In phytohemagglutinin (PHA) stimulated cultures it may inhibit DNA biosynthesis or exert augmentative effects on this process dependent on the composition of the culture medium.

Animals↗