Biomedical subjects
Publications and source records attributed to L Wiśniewski.
Two new cases of 9p- syndrome are presented. Two girls have the monosomy of 9p with several clinical features typical for this chromosomal anomaly. Patients' abnormalities are compared with Kuroki's description of this syndrome.
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Blastic transformation of phytohemagglutinin-stimulated lymphocytes in cultures containing various concentrations of homogenous alpha-fetoprotein (AFP) was studied. It was found that AFP in concentrations of 4-12 microgram/ml inhibits both blastic transformation and immunoglobulin release (IgA, IgG) in lymphocyte cultures. It is suggested that AFP plays an important role in immunoregulation during the fetal life.
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A case of ring chromosome was reported. By application of different techniques it was identified as 15 r. The boy 19 months old was of a short stature, small skull and slight psychomotoric retardation.
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Clinical signs of developmental anomalies found in the 49, XXXXY patients have been reported based on the author's case.
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