Biomedical subjects

Lien Chai Chiang

Publications and source records attributed to Lien Chai Chiang.

2 recordsLinked to original sources

PubMed2005

New gemacranolides from Eupatorium hualienense.

Phytochemical investigation of Eupatorium hualienense (C. H. Ou, S. W. Chung, C. I. Peng) has resulted in the isolation of the new sesquiterpene lactones 1-5, named eupahualins A-E, along with the known heliangolide eupasimplicin B (6). The structures of the isolated compounds were established through detailed spectral analyses, especially by means of 2D-NMR techniques. Compounds 1-4 and 6 showed significant activities against cell lines of human chronic myelogenous leukemia (K562) and human bone cancer (U2OS).

Antineoplastic Agents↗

PubMed2005

Bioactive pyranoxanthones from the roots of Calophyllum blancoi.

Phytochemical investigation of the roots of Calophyllum blancoi growing in Taiwan resulted in the isolation of three new pyranoxanthones, blancoxanthone (1), acetyl blancoxanthone (2) and 3-hydroxyblancoxanthone (3), in addition to two known pyranoxanthones, pyranojacaeubin (4) and caloxanthone (5). Structural characterization of the isolated compounds was determined by spectral analyses especially 2-D NMR. Biological study of the isolated xanthones revealed that blancoxanthone (1) exhibited significant anti-coronavirus activity.

Acetylation↗