The rectosigmoid bladder for urinary diversion.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to M A Ghoneim.
Explore the source record for details and available documents.
Intravenous digital subtraction angiography (IV-DSA) combined with excretory urography (IVU) were utilized to study the renal anatomy of 1000 potential live-kidney donors. In the entire series, 712 donors (71.2%) had bilateral single renal arteries, whereas 255 (25.5%) had unilateral multiple, 26 (2.6%) had bilateral multiple, and 7 (0.7%) had unilateral hypoplastic or absent renal arteries determined by IV-DSA. Major renal abnormalities that might be potentially significant for safe renal donation were detected in 76 donors (7.6%) by combined IV-DSA and IVU studies. In 10% of the potential donors, intraarterial digital subtraction angiography (IA-DSA) was required because of the equivocal results of IV-DSA. Of the 1000 potential donors, 700 underwent nephrectomy and the number of renal arteries at nephrectomy was compared with both IV-DSA and IA-DSA reports. Analysis of data revealed a sensitivity of 96% vs 95%, a specificity of 57% vs 75% and an overall accuracy 93% vs 90% for IV-DSA and IA-DSA, respectively, both IV-DSA and IA-DSA were accurate enough in identification of single renal arteries. However, the accuracy of IA-DSA was better than that of IV-DSA in visualization of double (84% vs 64%) and triple (66% vs 33%) renal arteries. It is concluded that IV-DSA combined with IVU is an effective technique for the evaluation of potential kidney donors. In cases where IV-DSA is equivocal, we recommend confirming IA-DSA.
Modern information technology offers new opportunities for the storage and manipulation of hospital information. A computer-based hospital information system dedicated to urology and nephrology was designed and developed in our centre. It involves in principle, the employment of a program that allows the analysis of non-restricted non-codified texts, for the retrieval and processing of clinical data, and operation by non-computer specialized hospital staff. This Hospital Information System now plays a vital role for the provision of an efficient, good quality service and is used now in daily routine and research work in this hospital. This paper describes this specialized hospital information system.
Explore the source record for details and available documents.
A study was initiated in September 1976 to detect early bladder carcinoma by selective cytologic screening in a rural Egyptian population infested with Schistosoma haematobium. All persons in a high-risk group, i.e., farmers aged 20 years and above, and selected persons from two low-risk groups were screened. Bladder carcinoma was detected in 11 patients among the 4,769 individuals screened in the high-risk group, for a yield of 2.3 per 1,000. No tumors were detected in the 3,975 individuals in the low-risk groups. Cytologically diagnosed tumors were verified by histology in all cases. One of the detected tumors in a female was found to be metastatic from carcinoma of the cervix. The primary tumors included five squamous cell carcinomas, four transitional cell carcinomas and one undifferentiated carcinoma. Seven of the tumors were at early stages, including three noninvasive (TIS) and four superficial (T1 and T2) ones. This investigation indicates that selective cytologic screening in the high-risk group in Egypt is feasible and effective for the early detection of bladder carcinoma associated with schistosomiasis.
Thirty Syrian golden hamsters were infected with Schistosoma mansoni and 10 were used as negative controls. Hamsters were infected by 50 cercaria; 15 were treated by praziquantil in doses of 100 mg/kg at 12, 13, 14 and 15 weeks postinfection, and 15 hamsters were left as positive control. Five from each subgroup were sacrificed at 24, 28 and 32 weeks postinfection. Animals were subjected to weekly analysis for total plasma protein, serum creatinine, albumin, cholesterol, 24-hour urine volume, and urinary total protein excretion. At the end point, animals were sacrificed and the mesenteric venous plexus was explored for adult worms. Kidney and liver specimens were examined by light microscopy, immunofluorescence microscopy, and electron microscopy. Complete parasite eradication was achieved in treated animals. Although there were significantly higher plasma total protein, albumin, and lower cholesterol in the treated group, there were no significant differences in proteinuria or renal histopathologic changes between treated and untreated animals. We conclude that in golden hamsters, with complete and early parasite eradication no regression occurs in S. mansoni-related nephropathy. Moreover, we suggest that in this glomerulopathy, short exposure to an antigen may be sufficient to set in motion a cascade of events which is irreversible and which leads to permanent glomerular damage.