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Biomedical subjects

M A Gonzalez

Publications and source records attributed to M A Gonzalez.

82 records · Page 5Linked to original sources
PubMedDate not supplied

Digitization of medical documents: an X-Windows application for fast scanning.

This paper deals with digitization, using a commercial scanner, of medical documents as still images for introduction into a computer-based Information System. Document management involves storing, editing and transmission. This task has usually been approached from the perspective of the difficulties posed by radiologic images because of their indisputable qualitative and quantitative significance. However, healthcare activities require the management of many other types of documents and involve the requirements of numerous users. One key to document management will be the availability of a digitizer to deal with the greatest possible number of different types of documents. This paper describes the relevant aspects of documents and the technical specifications that digitizers must fulfill. The concept of document type is introduced as the ideal set of digitizing parameters for a given document. The use of document type parameters can drastically reduce the time the user spends in scanning sessions. Presentation is made of an application based on Unix, X-Windows and OSF/Motif, with a GPIB interface, implemented around the document type concept. Finally, the results of the evaluation of the application are presented, focusing on the user interface, as well as on the viewing of color images in an X-Windows environment and the use of lossy algorithms in the compression of medical images.

Database Management Systems↗
PubMedDate not supplied

Use of an ATP-supplemented medium for the conservation of human semen and the effect of caffeine on the motility of preserved sperm. Results in artificial insemination.

Human semen can be preserved at 4 degrees C in an artificial medium containing 15% ATP-MgCl2 for up to 5 d. This method has been applied to samples from subjects with either normal or abnormal semen. After the conservation period the recovery of sperm motility observed was good when low doses of caffeine (3.5 or 7.0 mM) were added.

Adenosine Triphosphate↗
PubMedDate not supplied

Role of atrial natriuretic peptide on calcium channel mechanisms involved in catecholamine release from bovine adrenal medulla.

The role of the atrial natriuretic peptide on calcium channel mechanisms involved in catecholamine release was studied in the perfused bovine adrenal medulla. The atrial natriuretic peptide (1 nM and 10 nM) did not modify the spontaneous release of catecholamines. Ten nM of atrial natriuretic peptide decreased the output of catecholamines induced by acetylcholine, KCl-depolarizing solutions and angiotensin II. It was ineffective to modify the catecholamine release when calcium channels were blocked or in the presence of calcium-free media. Moreover, the deprivation of the ion calcium in the media decreased the catecholamine release induced by KCl to a lowest level, despite the presence of atrial natriuretic peptide in the perfusate. In conclusion, atrial natriuretic peptide inhibited the induced secretion of catecholamines in the bovine adrenal medulla and interfered as a partial blocker with calcium-dependent mechanisms.

Acetylcholine↗
PubMedDate not supplied

[Coxsackie B4 infection, myopericarditis and diabetes mellitus].

The authors described a case of acute miopericarditis with evolution towards dilated cardiomiopathy, secondary to Coxsackie B4 infection, in a patient developing a concomitant insulin dependent diabetes (DIDM), admitted to be also an expression of this infection. The pathogenesis and the immunological basis of this aggression is discussed and some therapeutic considerations made.

Coxsackievirus Infections↗
PubMedDate not supplied

Immunohistochemical location of S-100 and glial fibrillary acidic proteins in salivary gland pleomorphic adenomas.

The S-100 protein is a low molecular weight protein which has been isolated mainly in mammalian brain cells. Glial fibrillary acidic protein is one of the five types of intermediate filaments described to date. We used immunohistochemical methods to study the expression in this patterns of expression of these two proteins in pleomorphic adenoma of the salivary glands, in an attempt to explain their tumor and to elucidate the origin of this complex neoplasm of the salivary glands.

Adenoma, Pleomorphic↗
PubMedDate not supplied

[Neoplastic hypercoagulability. Apropos of 2 cases with Trousseau syndrome].

The authors describe two cases with venous thromboembolism and neoplasia (ovary and stomach), which also showed evidence of arterial thromboembolic phenomena--cerebrovascular disease in the 1st case and acute myocardial infarction in the 2nd case--favouring the existence of nonbacterial thrombotic endocarditis. This presentation of neoplastic hypercoagulability is frequently underrated in clinical practice. Pathogenesis, clinical manifestations, etiology, and therapeutics of these syndromes are discussed in relation to the presented cases.

Aged↗
PubMedDate not supplied

[Assessment of glomerular filtration rate in a hospital population. Comparison of two methods].

OBJECTIVES: This study was undertaken to assess the value of Cockroft-Gault Formula (FCG) in the patients of an Internal Medicine ward. METHODS: FCG was compared with creatinine clearance (DC) adjusted for corporal area. Serum creatinine was measured after 24 h urine collection and 8 h fast. By the subtraction of FCG from DC, the variable difference (DIF) was calculated. FCG was calculated using total body weight (PT) and lean body weight (PS). All patients were included unless they had renal failure. RESULTS: Renal function was calculated in 92 patients, 33 women and 59 men. Mean age was 60.8 +/- 17.9 (13-87). Mean FCG (64.7 +/- 27.4) and mean DC (68.4 +/- 32.6) were not significantly different and a correlation between them was found (r = 0.68; p < 0.001). Using PS to estimate FCG the correlation coefficient was increased to 0.75 (p < 0.001). DC and FCG using PT or PS correlated inversely with age (r = 0.59; r = 0.53; r = 0.66, respectively; p < 00.1). In a cluster analysis model we could find that for extremes of renal function FCG overestimated (DIF = -10.4 +/- 13.3) or underestimated (DIF = 29.8 +/- 29.7) DC. The main influence for the difference between the two methods was body weight (r = -0.69; p < 0.001). The distribution by diagnosis led to two classes of patients for whom DIF was significantly different (p < 0.02), and body weight was the main factor. CONCLUSION: Cockroft-Gault formula, although correlating with creatinine clearance, over or underestimates creatinine clearance for extremes of renal function. Age and body weight were the main factors for the differences found between the two methods.

Adolescent↗