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Biomedical subjects

M Angel

Publications and source records attributed to M Angel.

At least 19 recordsLinked to original sources
PubMed1991

Topography and morphology of retinal ganglion cells in Falconiforms: a study on predatory and carrion-eating birds.

The topographic distribution of retinal ganglion cells and their cell body size have been studied in five Falconiform species, including predatory (chilean eagle Buteo fuscenses australis, and sparrow hawk Falco sparverius) and carrion-eating (chimango caracara Milvago chimango; condor Vultur gryphus, and black vulture Coragyps atratus) birds. All these species had a well defined nasal fovea and a horizontal streak. Instead of a temporal fovea as in eagles and hawks, an afoveate temporal area is present in chimango, condor, and vulture. The highest ganglion cell density was found in the nasal fovea of Falco and Buteo with 65,000 and 62,000 cells/mm2, respectively. A negative correlation between ganglion cell density and cell body size was found in all the species studied. The specializations of the temporal retina showed a rather homogenous population of medium sized neurons, while the nasal foveas showed a homogeneous population of smaller ganglion cells. Finally, the peripheral retina showed a heterogeneous population of large, medium, and small ganglion cells. Predatory behavior appears to be closely related to foveal specializations, and is best exemplified in the eagle and hawk and to a lesser extent in the chimango.

Animals↗
PubMed1991

Velocardiofacial (Shprintzen) syndrome: an important syndrome for the dysmorphologist to recognise.

We report the dysmorphological, genetic, and speech therapy aspects of 38 cases of velocardiofacial syndrome presenting to a craniofacial clinic and a specialised children's hospital, to indicate a relatively low incidence of clefting, good response to pharyngoplasty, considerable variability of the syndrome, and two further familial cases. We emphasise the low index of suspicion by paediatricians and paediatric subspecialists which resulted in delayed diagnosis and delayed treatment for the hypernasal speech and velopharyngeal insufficiency for periods of four months to seven years.

Abnormalities, Multiple↗
PubMed1991

[A new demographic classification of the family for the use in primary health care].

The approach to the health-disease problem in the family requires a knowledge of demographic features. We propose a demographic classification based on the nuclear family. In addition to the extensive and single-parent families, the lack of family and the familial equivalents we subdivide the nuclear family depending on whether it has close relatives or not, the number of children, the existence of extended family or not, with relatives or aggregates, and the binuclear families or those of divorced people. On this basis, we have evaluated the demographic distribution of 917 families from the basic health areas of Albaicín and Cartuja in Granada, the Valle de Jaén, and Telde in Las Palmas. We have found the predominance of the nuclear family (76.8%) over the extensive (5.2%), as well as the relevance of the single-parent (8.9%) and the lack of family (7.7%) types. Among nuclear families, those with relatives in near areas come first (62.2%), followed by the extended type (19.6%). There is a remarkably low rate of numerous families (9.3%), while binuclear families are exceptional. As familial demography is a factor to be considered in clinical practice owing to its influence in the familial function and resources, we propose the routine use of this classification in the family history.

Demography↗
PubMed1987

Diagnosis of lung carcinoid with cutaneous hyperpigmentation eight years after bilateral adrenalectomy.

A 26-yr-old male was submitted to bilateral adrenalectomy in 1977 for Cushing's syndrome. Some months later he developed intense skin hyperpigmentation together with increased ACTH levels (149 to 4000 ng/l). The sellar region was always normal in X-ray studies. In April 1985, when the patient complained of chest pain, a chest x-ray showed a polycyclic mass in the upper left lobe of the lung. ACTH ranged from 20,000 to 100,000 ng/l, with no response to CRF or cyproheptadine administration. Urinary 5-OH-indolacetic acid was negative. Thoracotomy was performed in July 1985 with resection of two intrapulmonary masses. Histologic study demonstrated a carcinoid tumor, with positive neuron-specific enolase and ACTH immunochemical stain. ACTH concentration in tumoral tissue was 91 pg/g tissue. After surgery ACTH fell dramatically to 37 ng/l, and has remained at this level since then, associated with resolution of the skin hyperpigmentation.

Adrenalectomy↗
PubMed1979

[Sarcoidosis, toxic thyroid adenoma, and De Quervain's thyroiditis. Association or coincidence (author's transl)].

The case of an association of three well-differentiated pathologies is reported. A 40-year-old woman with a toxic thyroid adenoma developed acute polyarthritis during the course of the disease. The articular symptoms together with chest X-rays and a consistently negative PPD (1:100) were suggestive of sarcoidosis. This was later confirmed by the discovery of non-caseating granulomas in the liver and superficial lymph nodes, and by a positive Kveim's test. Histopathologic examination of the thyroid gland confirmed the existence of the adenoma. Sarcoid infiltration was not observed, but on the other hand the typical images of subacute granulomatous thyroiditis (De Quervain's thyroiditis) were discovered.

Acute Disease↗