PubMed Health⌕ Search

Biomedical subjects

M Aubert

Publications and source records attributed to M Aubert.

174 records · Page 10Linked to original sources
PubMedDate not supplied

[Left superior veina cava and endocardial stimulation (author's transl)].

A left superior veina cava may be troublesome for endocardial lead's placement during permanent pace maker's implantation. We have operated upon one patient with this anomaly. We report the anatomic frequency of this congenital malformation and the technics used to obtain a satisfactory permanent pacing.

Aged↗
PubMedDate not supplied

[Acute pancreatitis].

Explore the source record for details and available documents.

Acute Disease↗
PubMedDate not supplied

[Benign hypoglycemiant pleural tumors. Report on two cases].

Two cases of hypoglycemiant pleural fibroma are reported: -- the first case, in a patient with sarcoidosis, was diagnosed following the onset of neuropsychic manifestations due to hypoglycemia; --the second case, much more atypical, was a patient with an enormous pleural tumor affecting cardiorespiratory function to such a degree that almost total incapacity ensued: the hypoglycemia was detected during routine pre-operative investigations. Various extrathoracic manifestations accompany these tumors: osteo-articular (present in 1 patient), and thyroidal (present in both cases). The various mechanisms proposed to explain the development of hypoglycemia in patients with certain extra-pancreatic tumors are reviewed.

Aged↗
PubMedDate not supplied

[Our experience with thoracoscopy (author's transl)].

The last two years, we carried out 25 thoracoscopies in 26 patients. The examination was not possible in 2 cases, because of severe adhesions, in one case neoplastic and in the other, fibrous. One patient had a bilateral exploration on two separate occasions. All these examinations were carried out under general anesthesia with differential intubation or, on occasion, tracheal intubation. The first 15 cases were carried out using the rigid bronchoscope with a cold light; the subsequent examinations were carried out using the Storz thoracoscope. From a diagnostic point of view, our patients broke down in the following manner: -metastatic pleurisies - 6, -pleural effusion in reaction to bronchial carcinoma -2, -post-radiotherapic pleural effusion - 1, -benign asbestos pleurisy -5, -cirrhotic pleural effusion - 1, -inflammatory pleurisy - 9. We carried out talcum adhesion of the pleura in only 4 cases : 2 cases of neoplastic pleurisy, 1 post-radiotherapy pleurisy, and 1 inflammatory pleurisy. There were 2 infectious complications in this series : one in a patient with diabetes, leading, indirectly, to death. The second was cured by pleuro-pulmonary decortication.

Chronic Disease↗
PubMedDate not supplied

[Pancoast and Tobias syndrome of benign etiology (author's transl)].

The authors report a case of Pancoast and Tobias syndrome due to a hydatic cyst on the apex of the left lung. This parasitosis is together with tuberculosis and least infrequent benign etiology of Pancoast and Tobias syndrome. In our observation it was a young cyst without complications as opposed to previously reported cases.

Adult↗
PubMedDate not supplied

Large trials vs meta-analysis of smaller trials: how do their results compare?

OBJECTIVE: To evaluate the results of large clinical trials vs the pooled results of smaller trials. DATA IDENTIFICATION: Meta-analyses with at least 1 "large" study were identified from the Cochrane Pregnancy and Childbirth Database and from MEDLINE (1966-1995). STUDY SELECTION: We used a sample size approach to select 79 meta-analyses with at least 1 large study of 1000 or more patients. We used a statistical power approach to select 61 meta-analyses with at least 1 large study based on statistical power considerations. DATA EXTRACTION: The outcome of interest for each meta-analysis was the primary one stated in the original publication or, when not clearly specified, was decided on clinically. DATA SYNTHESIS: By random effects calculations, we found agreement between large and smaller trials in 90% of the meta-analyses selected by the sample size approach and in 82% of the meta-analyses selected by the statistical power approach. Twice as many disagreements appeared when the variability among large studies and among smaller studies was not considered (ie, fixed effects calculations). Of the 15 disagreements between results of large and smaller trials using the random effects model, plausible explanations were identified in 10 meta-analyses: 5 with differences in the control rate of events between large and smaller trials, 4 with specific protocol or study differences, and 1 with potential publication bias. Two other disagreements were not clinically important, and tentative reasons could be identified for 2 of the remaining 3 disagreements. CONCLUSIONS: Results of smaller studies are usually compatible with the results of large studies, but discrepancies do occur even when the diversity among both large studies and smaller studies is considered. Clinically important differences without a potential explanation are extremely uncommon. Future research should further examine sources of heterogeneity between the results of large and smaller trials.

Bias↗
PubMedDate not supplied

Comparison of the effectiveness of two protocols of antirabies bait distribution for foxes (Vulpes vulpes).

In a plateau and hill region of France (the Doubs), two protocols of rabies vaccine bait distribution targeted at foxes were compared: helicopter distribution of vaccine baits alone (control zone) and a combined aerial distribution by helicopter with an additional deposit of vaccine baits at fox den entrances by foot (test zone). In the test zone covering an area of 436 km2, baits were distributed by helicopter at a rate of 13.4 baits/km2. Additionally, an average of 11.4 vaccine baits at the entrances of 871 fox dens were terrestrially distributed by 110 persons (9,964 baits). In this test zone, 90% of the young foxes were marked with tetracycline which permitted estimation of the bait consumption; however, only 38% had significant titre of rabies antibodies and less than one fox cub per 2.4 of those having consumed at least one bait were immunized. In the control zone, these percentages were significantly lower: respectively, 35 and 17% and one fox cub per 4.2. The relative lack of benefit between bait uptake and rate of immunological response may be due to maternal immunity which could have interfered with fox cub active immunization. A booster effect following a second distribution of baits by foot may be suggested in both adult foxes and their offspring. That these baits needed to be terrestrially distributed in order to obtain a booster effect is uncertain. Terrestrial distribution at fox den entrances is difficult to do and entails additional expenses not incurred in aerial distribution. The cost of terrestrial vaccination is 3.5 times higher than classical aerial vaccination and takes 63.5 times longer. A cost effective analysis of this type of supplementary terrestrial intervention determined that bait deposit at den entrances can be recommended for restricted areas, where residual focii exist, as a complement to the aerial distribution of baits.

Aircraft↗