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Biomedical subjects

M Büttner

Publications and source records attributed to M Büttner.

At least 109 records · Page 6Linked to original sources

[Diagnostic therapeutic problems of defibrination syndrome in shock, sepsis, and neonatal hypoxia (author's transl)].

The diagnosis of defibrination syndrome in shock, sepsis and neonatal hypoxia is based, in addition to the clinical picture, upon a few parameters of the hemostatic system, which, in part as global tests, provide information about the course of coagulation. The parameters measured are partial thromboplastin time, thromboplastin time, plasma thrombin time, fibrinogen, thrombin-coagulase and reptilase times as well as platelet count. Normal values of these laboratory parameters were established for healthy newborns 1--5 days of age, and for healthy adults. It is suggested that especially partial thromboplastin time, the thrombin-coagulase and reptilase times, the latter influenced by fibrinolysis cleavage products, are representative for the tentative diagnosis of disseminated intravascular coagulation with fibrinolysis syndrome (DICFS). The platelet fall often lags 1--2 days behind the event. Moreover normal values for newborns, are markedly higher than those for older children or adults. In the presence of DICFS, a low-dose heparin therapy is immediately initiated. If completed defibrination is manifest, therapy is supplemented with urokinase and streptokinase, For DICFS with congenital sepsis, an exchange transfusion with heparinized fresh blood is the treatment of choice.

Asphyxia Neonatorum↗

[Results of serial studies in basle children after 12 years of water fluoridation and 4 years of prophylaxis in nurseries and schools].

The public water supply of Basel has been fluoridated to a content of 1 ppm since May 1962. A distinct reduction of caries could be observed since. The last four years have shown a decrease of caries incidence too, and the merit for this should be given to the prophylaxis department. Particularly the youngest individuals have benefited from this prophylaxis, because it has been intensified and its scope widened.

Child↗