Reducing genetic risk from x rays.
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Biomedical subjects
Publications and source records attributed to M Barnett.
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Various aziridine derivatives derived from diamines were studied in several biological systems to evaluate their effects on reproduction and as potential mutagens. Considerable variations in the biological activities of these compounds were seen among animal species and among the varied chemical structures. In general, mutagenic responses paralleled the antifertility effects in mice and houseflies and the anticancer effects in mice. The lack of an antifertility effect by N,N'-bis(aziridinylacetyl)-1,8-octamethylenediamine in the rat was quite unexpected in view of its chemosterilant activity in houseflies and mice.
Data from non random groups of deliveries with some identical clinical factors were compared and certain conclusions are suggested. Most x-ray examinations which cause significant fetal exposure are pelvimetries. There appears to be no uniform set of indications for performing pelvimetry. Instead, the criteria seem to vary from hospital to hospital and even from physician to physician within the same hospital. A normal pelvimetry gives the physicina little confidence that a cesarean section will not be necessary. The duration of labor is not significantly altered by pelvimetry in those cases needing a cesarean section for cephalopelvic disproportion or following unsuccessful oxytocin stimulation.
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