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M Baudouy

Publications and source records attributed to M Baudouy.

At least 91 records · Page 5Linked to original sources
PubMed1985

[A method of processing information on cineangiography of the right ventricle].

This paper describes our experience in making a programme for computer processing of biplane right ventricular cineangiography for the measurement of volumes and analysis of wall motion. The volumes were determined by a method of integration to the geometric model of a triangular pyramid i.e. trunco-pyramidal (IM.TP). The classical ellipsoidal integration method i.e. trunco-conal (IM.TC) and biplane and monoplane planimetry based on the model of a triangular pyramid (PM.TP) were used as references. Nineteen post-mortem RV casts were used to validate the programme. The correlations between the true volumes and the angiographic measurements were excellent (r = greater than 0.99) with both methods of integration, very good (r = 0.99) using the biplane PM.TP and very satisfactory (r = 0.91) with the monoplane PM.TP. The line of regression was very close to unity with the IM.TP and 0.9 with the PM.TP; this indicates the excellent adaptation of the triangular pyramid model to the shape of the RV. The IM.TP was used in a group of 20 right ventriculographies of patients without cardiac disease: the following results were obtained: EDV = 70.3 +/- 6.6 cm3/m2; ESV = 31.7 +/- 3.9 m3/m2; systolic index = 38.6 +/- 4.5 cm3/m2; ejection fraction = 0.55 +/- 0.04. The correlation of the values of systolic index by cineangiography and thermodilution (39.9 +/- 5.7 cm3/m2) was good (r = 0.86; p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Blood Volume↗
PubMed1985

[Significance of ST segment depression in the precordial leads during the acute phase of inferior myocardial infarction].

Reciprocal changes of the ST segment in the acute phase of inferior myocardial infarction are common but their significance remain controversial. We studied this problem by comparing the ECG on admission of 83 patients with acute inferior myocardial infarction, with the clinical outcome and haemodynamic and angiographic data obtained on average 3 weeks after the onset of symptoms. Fifty nine patients (Group I) had ST depression greater than or equal to 1 mm in at least one of the leads V1 to V4; 24 patients (Group II) had no ST depression in this territory. The patients in Group I were older (59.6 +/- 6.4 vs 54 +/- 5.3 years, p less than 0.01), had higher total CPK (1 835 +/- 940 vs 875 +/- 305, p less than 0.01) and MB fractions (269 +/- 102 vs 95 +/- 35), more complications during the hospital period (80%, mainly haemodynamic vs 38%, p less than 0.01) and more severe left ventricular dysfunction: ejection fraction 52.2 +/- 6% vs 59.2 +/- 7%, p less than 0.05; cardiac index 2.75 +/- 0.4 l/min/m2 vs 3.25 +/- 0.3 l/min/m2, p less than 0.005). There was no difference in left ventricular wall motion between the groups on biplane angiography. However, coronary angiography showed left coronary disease to be more common in Group I (84%) than in Group II (37%), p less than 0.005. Left anterior descending and left circumflex disease was equally common. Patients with persistent ST depression after 48 hours had lower ejection fractions than those in whom it regressed within 48 hours.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMed1985

[Role of dihydralazine in the treatment of chronic cardiac insufficiency].

Dihydralazine, sold under the name of Nepressol, is the derivative of the hydrazinophthalazines used in France for the treatment of severe cardiac failure. The hydrazinophthalazines act in cardiac failure by decreasing systemic arterial resistance and increasing cardiac output without causing tachycardia or increasing myocardial contractility in normal or hypotensive subjects. The hydrazinophthalazines are metabolised by N-acetyl-transferase in the liver. The hepatic concentration of this enzyme is genetically determined. The immediate haemodynamic results observed with 100 to 300 mg/daily of Nepressol are impressive: an 86 p. 100 increase in cardiac output; a 75 p. 100 decrease in systemic valvular resistance; a 25 p. 100 fall in left ventricular filling pressures. These haemodynamic results are maintained at long-term (3 to 48 months). This treatment is associated with an improvement in symptoms and functional capacity. However, its efficacy in improving survival has not been demonstrated. Immunological complications giving rise to a lupic syndrome result only in biological changes and do not influence management.

Aged↗
PubMed1984

[Intracoronary thrombolysis in myocardial infarction].

In more than 70% of the cases thrombi in the coronary arteries responsible for myocardial infarction can be dissolved by intracoronary injection of a fibrinolytic agent. For the left ventricular function to improve thrombolysis must be performed within 4 hours of thrombus formation; when performed later, results are inconstant. The risks of arteriography and thrombolysis (mostly dysrhythmias and haemorrhage) are real but acceptable. The mortality rate is lower than with conventional treatment. Improvement in left ventricular global ejection fraction is more pronounced in cases with collateral circulation and when thrombolysis is performed at an early stage. Thrombosis recurs within a few days in 15-20% of the cases. This can be prevented by aorto-coronary bypass or transluminal dilation of the stenotic vessel with a balloon catheter, either of these being carried out very early in cases with tight stenosis or delayed when the stenosis is significant but not life-threatening. A multicentre trial should be set up to find out whether intracoronary thrombolysis improves long-term survival and prevents late complications. But even if this were true, it should still be demonstrated that the method is as effective and safe as intravenous thrombolysis.

Aged↗
PubMed1984

[Hemodynamic study during 48 hours of delayed-release isosorbide dinitrate (repeated oral administration) in the acute phase of myocardial infarction complicated by left ventricular insufficiency].

The aim of this study was to evaluate the haemodynamic effects of slow release isosorbide dinitrate (IDN) 40 mg oral preparation over a 48 hour period in patients with acute myocardial infarction complicated by left ventricular failure. Fourteen patients (8 male, 6 female) were treated by repeat dose ISD (8 hourly) and the haemodynamic changes were recorded at 1 hr, 2 hrs, 6 hrs, 12 hrs, 24 hrs, and 48 hrs. After 48 hours treatment the heart rate was unchanged; mean arterial blood pressure fell from 109.5 +/- 5.6 mmHg to 93.5 +/- 6.2 mmHg (-15%) (p less than 0.01). Cardiac index rose from 2.4 +/- 0.57 1/min/m2 to 2.8 +/- 0.65 1/min/m2 (+16%) (NS); diastolic pulmonary artery pressure fell from 22.5 +/- 7.07 mmHg to 13.7 +/- 4.5 mmHg (-39%) (p less than 0.003); systolic pulmonary artery pressure fell from 40.5 +/- 12.2 mmHg to 28.6 +/- 11.6 mmHg (-30%) (NS). Systemic vascular resistance fell from 2 095.2 +/- 63 dynes/s/cm5 to 1 537 +/- 60 dynes/s/cm5 (-22.3%) (NS). Finally, total pulmonary resistance fell from 561.9 +/- 15 dynes/s/cm5 to 301.9 +/- 14.5 dynes/s/cm5 (-47%) (p less than 0.003). The most valuable effect was therefore the reduction in left ventricular filling pressures which was maximal after about 48 hours. Two groups of patients were identified according to the clinical outcome. The patients in Group I (11 cases) were improved by the fall in diastolic pulmonary artery pressure, the rise in cardiac index and the reduction of systemic valvular resistance.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1982

[Implantation of permanent cardiac pacing electrodes by the retropectoral transvenous approach. Results of a series of 152 cases].

When the cephalic vein is unsuitable for the introduction of pacing electrodes, the retropectoral veins near the external border of pectoralis major near its subclavian attachment, approached through the same incision, may provide a suitable alternative. It was not possible to catheterise the cephalic vein in 23,8% of 756 consecutive implantations of endocavitary pacing electrodes. The retropectoral veins were looked for in 172 cases and found and used in 159 cases (92,4%). This percentage of success increased to 97,6% in the latter 83 attempts. These veins are usually very distensible. No complications or accidents were recorded. The only disadvantage was the relatively long dissection time. The stability of the pacing electrodes with this approach was excellent as reoperation was only required in 3% of cases (2 displacements and 3 exit blocks or pericardial migrations). This approach is therefore practicable in the large majority of cases in which the cephalic vein cannot be used. The multiplicity of the retropectoral veins should allow the introduction of two electrodes if sequential atrioventricular pacing were to be chosen. In addition, this approach would be useful when an atrial pacing electrode is to be added to a preexisting ventricular pacing electrode and one hesitates to puncture the subclavian vein because of the risk of damaging the electrode already in place. When direct subclavian puncture is the technique of choice of the operator, the retropectoral veins may be used when the subclavian approach is contraindicated or impossible. In any case, denudation of the retropectoral veins leads to fewer incidents than when the latter approach is used.

Electrodes, Implanted↗
PubMed1980

Effects of an interpolated premature ventricular contraction on the AV conduction of the subsequent premature atrial depolarization. An apparent facilitation.

Nodal conduction is usually studied by tracing the H1 H2 on function of A1 A2 curves. If one interpolates a PVC before A1, there is a decrease in H1 H2. This might be explained by an A1 H1 interval lengthening (delta A1 H1). This study was done on 14 consecutive patients in whom a PVC can be interpolated (blocked at the A-V junction). In the majority of these patients, there is a downward and a right hand shift in the curve after an interpolated PVC. On other hand, the curves representing the sum H1 H2 + delta A1 H1 on function of A1 A2 were shifted upward and to the right in 12 of the 14 patients. This indicates inhibition which manifests itself not only by an ERP increase but also by an A2 H2 increase.

Arrhythmias, Cardiac↗
PubMed1979

[Aneurysm of the interauricular septum by hernia of Vieussens' valve, and suspected coronary embolism].

During the hemodynamic evaluation of a young patient with heart failure whose electrocardiogram showed sequels of anterior necrosis, an aneurysm of the fossa ovalis was seen at cineangiography. Selective coronary angiography showed an interruption of filling of the anterior interventricular artery just distal to the branching of the first septal artery: it raised therefore the possibility of the embolic origin of that myocardial infarction. In connection with this case study, angiographic aspect, pathogenesis and the embolic role of the aneurysm of the fossa ovalis were discussed.

Adult↗
PubMed1977

[Paradoxical atrioventricular block within the bundle of His].

We have been able to record an atrio-ventricular block dependent upon bradycardia, but also no tachycardia, in a patient of 76 who presented with syncopal attacks. The basal electrocardiogram showed no significant delay in atrio-ventricular or intraventricular conduction. Intracavitary electrophysiological investigation allowed us to localise the site of this block in the main trunk of the bundle of His; we also established, under basal conduction conditions, a first degree block with an exactly similar relationship to the duration of the preceding diastole.

Aged↗