An individual has been found whose red blood cells type as Sc:-1,-2, and do not absorb or yield on elution, anti-Sc1 or anti-Sc2. The patient produced an antibody reacting with all red blood cells, except those that were Sc:-1,-2. The antibody, here called anti-Sc3, was shown not to contain separable specificities when absorption studies were performed with Sc:-1,2 and Sc:1,-2 red blood cells. It appears that all Sc:1 or Sc:2 red blood cells are also Sc:3, while those that are Sc:-1,-2 are Sc:-3. A family study did not reveal the genetic background responsible for this Sc:-1,-2 phenotype.

Aged↗

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Parental distress during pediatric leukemia and posttraumatic stress symptoms (PTSS) after treatment ends.

OBJECTIVE: To evaluate prospectively the association between parental anxiety during treatment for childhood leukemia and posttraumatic stress symptoms (PTSS) after treatment ends. A secondary goal is to explore concurrent variables associated with parental avoidance after treatment ends. METHODS: This is a longitudinal follow-up study of 113 parents of children treated for leukemia who previously participated in a study of procedural distress during treatment. Data included parental self-report questionnaires completed during treatment and after treatment. RESULTS: Using hierarchical multiple regression, we found anxiety during treatment to be a significant predictor of later PTSS for mothers, but not fathers. Anxiety, self-efficacy, posttraumatic growth and length of time since treatment ended were associated with parental avoidance. CONCLUSIONS: Highly anxious parents are at risk for PTSS and may benefit from approaches that decrease anxiety during treatment and afterward. Enhancing self-efficacy related to follow-up care and identifying positive aspects of the traumatic experiences are suggested as treatment approaches for families after cancer treatment.

Adaptation, Psychological↗

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Our role in the future ... what laboratory professionals think the future holds for them.

Explore the source record for details and available documents.

Consultants↗

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Managing human resources in a changing health-care environment.

Managing human resources in this era of precipitous change poses one of the most difficult challenges and opportunities for leaders in the clinical laboratory. Shifts in health systems integration, cost control, patient-focused managed care, and provider changes have led to trends which fundamentally alter the way in which clinical laboratory services are organized, provided, and funded. To be successful change agents, laboratory managers must understand the cycle of human resource development and how people adopt change. They must embrace a systems thinking perspective and develop strategic leadership skills to share a vision of what the laboratory of the future will be. These new, advanced human resource management skills can be acquired through a variety of formal and informal learning experience.

Clinical Competence↗

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Clinical nursing research and quality assurance: integration for improved patient care.

Understanding how nursing quality assurance and research programs are similar, yet different, is the first step towards enabling nurse managers to integrate the two programs. Blending research findings and research methods into the quality assurance process is one method of accomplishing integration. Other strategies include setting standards for nursing research and including instruments with known validity and reliability in patient care planning and patient assessment. Improving the scientific basis of nursing practice and the quality of patient care are viable outcomes.

Clinical Nursing Research↗