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M Blunt

Publications and source records attributed to M Blunt.

15 recordsLinked to original sources

Seasonal variation in admission rates to intensive care units.

Intensive care physicians perceive that there is seasonal variation in the number of admissions to critical care services. There is, however, little published evidence to support this belief. Data were therefore collected from five adjacent critical care units in the eastern region over a period of 8 years, in order to quantify any seasonal variation that may exist. Data on 16 355 critically ill patients were obtained between 1992 and 2000. Analysis showed clear winter peaks; December had a 30% higher admission rate than the quietest month, February. There was a small, but increasing, summer peak. The admission rate also exhibits an increasing linear trend, equivalent to a 6.6% annual increase in admissions per critical care bed. We conclude that there is significant seasonal variation in critical care activity, and that this is important to consider when planning services.

Adult↗

Why KY?

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Gels↗

A comparison of the effects of dopexamine and prostacyclin in systemic inflammatory response syndrome.

Forty critically ill patients fulfilling the definitions of systemic inflammatory response syndrome were enrolled in a double-blind cross-over interventional study assessing the effects of dopexamine and prostacyclin on splanchnic perfusion, cardiovascular function and oxygen flux. The cross-over design involved either dopexamine (1.25 micrograms.kg-1.min-1) or prostacyclin (0.5 ng.kg-1.min-1) being infused for 6 h followed by a 12-h washout period prior to an identical infusion sequence using the other agent. Preliminary analysis revealed a significant period effect, so data from the second infusion period were excluded from further analysis. Dopexamine caused a significant increase in heart rate (116 vs. 106 beat.min-1), and urine output (103 vs. 69 ml.h-1). Dopexamine produced a significant increase in oxygen delivery (infusion 548 ml O2.min-1.m-2; no infusion 492 ml O2.min-1.m-2) while prostacyclin caused a decrease (infusion 460 ml O2.min-1.m-2; no infusion 547 ml O2.min-1.m-2). The results indicate that dopexamine improves oxygen delivery and urine output more effectively than prostacyclin.

Adrenergic beta-Agonists↗

Hydrocarbon Drainage along Corners of Noncircular Capillaries

An approximate solution for liquid flow along corners of noncircular capillaries is proposed that relates the flow resistance to the geometry of a capillary and to the contact angle of the interfaces. The theory predicts liquid flow rates for both two-phase (hydrocarbon/air) and three-phase (hydrocarbon/air/water) drainage. This solution is found to be superior to other expressions in the literature. Drainage rates of two different hydrocarbons along corners of square capillaries are measured with both air and water as stationary phases. The new solution was used to predict the measured hydrocarbon drainage rates successfully. Comparison of the measured and predicted drainage rates indicates that a free boundary is appropriate for the air/hydrocarbon interface and a no-flow boundary condition is valid for the water/hydrocarbon interface. The effect of spreading coefficient on drainage rates is also demonstrated by the measurements and is compared with the proposed solution. A brief discussion of three-phase relative permeabilities is offered based on the measured drainage rates and proposed solution.

Journal Article↗

Routine human immunodeficiency virus infection screening of women requesting induced first-trimester abortion in an inner-city population.

Infection with the human immunodeficiency virus (HIV) among reproductive-age women occurs disproportionately among inner-city minority populations. These women are at risk because of intravenous drug abuse and heterosexual transmission from partners infected through drug abuse. From July 1, 1988 to December 31, 1988, we conducted routine voluntary screening for HIV antibody among 923 women who requested induced first-trimester abortion at Grady Memorial Hospital. Eight (8.7 per 1000) women were seropositive on repeat enzyme-linked immunosorbent assay and Western blot testing. Two infected women had had heterosexual contact with a person at risk for HIV infection, two others reported "crack" cocaine use, and four acknowledged no risk factors. Thirteen percent of seronegative women reported risk factors for HIV infection. Nearly all women consented to HIV testing, and most completed the risk-behavior questionnaire. These data suggest that women seeking first-trimester abortion at our hospital are at risk for HIV infection.

Abortion Applicants↗