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Biomedical subjects

M Bridle

Publications and source records attributed to M Bridle.

6 recordsLinked to original sources

Identification of human immunodeficiency virus type 2 in a New Zealand resident.

AIMS: To determine the human immunodeficiency virus (HIV) types infecting a West African immigrant to New Zealand. To develop an HIV type 2 specific polymerase chain reaction (PCR). METHODS: The HIV antibody status of the patient was determined using both HIV-1 and dual HIV-1 and 2 enzyme immuno assays (EIA). Western blot with HIV-2 and HIV-1 and 2 strips was used as a confirmatory assay. DNA from white blood cells was extracted and HIV proviral DNA amplified using either primers specific to the HIV-2 gag region (VB305 and VB312) or to HIV-1 gag (SK38/39) and env (SK68/69) regions. Amplified products were electrophoretically resolved, southern blotted and probed with specific oligonucleotide probes. RESULTS: The patient serum was strongly reactive for HIV antibodies by EIA and showed multiple reactivity when tested by western blot against both HIV-1 and HIV-2 proteins. DNA was only amplified with primers specific to HIV-2 and the 298 bp product hybridized with an HIV-2 specific probe. No HIV-1 DNA was amplified from the patient. CONCLUSION: This individual is infected with HIV-2 and has most likely developed antibodies that cross-react with HIV-1. We believe this is the first report of an HIV-2 infected individual in New Zealand.

AIDS Serodiagnosis↗

A survey of Canadian occupational therapy private practice.

This descriptive study provides an overview of the business structure and function of occupational therapy private practitioners in Canada. Aspects covered include basic demographic information, practice issues defining operational aspects of the business, financial issues including initial investment and fee structures, and other miscellaneous business issues. Some implications for the national and provincial professional organizations arose from the results and are presented in the discussion.

Age Factors↗

Therapeutic plasmapheresis by continuous flow cnetrifugation.

This report reviews the experience at Auckland Hospital with continuous flow centrifugation as a mean of carrying out therapeutic plasmapheresis. Over a three year period from August 1975, 26 patients, most with dysproteinaemias or Goodpasture's syndrome, were treated with a total of 260 therapeutic procedures.

Adolescent↗

Community placements.

A pilot study at Queen's University on the use of community facilities for undergraduate clinical training is described. The objectives of this project were to provide broadening experiences for students outside the institutional model, and to increase the number of available placements. From both the faculty and student points of view, the project is considered a success and is being expanded. The authors suggest that the future therapist must be prepared for community practice and recommend the inclusion of similar experiences in all undergraduate occupational therapy programmes.

Community Health Services↗