PubMed Health⌕ Search

Biomedical subjects

M Caselli

Publications and source records attributed to M Caselli.

78 records · Page 5Linked to original sources

"Cervia Working Group Report": guidelines on the diagnosis and treatment of Helicobacter pylori infection.

Different national attitudes exist between countries in Europe concerning eradication of Helicobacter pylori infection due to the wide differences in Helicobacter pylori prevalence, gastric cancer risk, bacterial resistance to antibiotics, health care systems and financial resources. The Cervia Working Group Report has been established in order to fill the gap in the absence of National Guidelines in Italy concerning the diagnosis and treatment of Helicobacter pylori infection. The recommendations made are, by and large, similar to the European Guidelines but differ slightly with regard to the "test-and-treat" approach to young dyspeptics without sinister symptoms. In the absence of a national validation of this strategy a case-by-case assessment of dyspepsia has been promoted, both at primary care and specialist level. Another area of partial disagreement concerns the eradication of Helicobacter pylori in patients undergoing long-term proton pump inhibitor treatment which has not been generally recommended as scientific evidence in support of this policy is at present rather weak.

Anti-Bacterial Agents↗

Fhit protein expression in human gastric cancer and related precancerous lesions.

The FHIT gene is altered in several types of tumors and abnormal expression of Fhit protein have also been reported in some preneoplastic lesions. We have determined the Fhit expression on histological samples of 26 patients affected by preneoplastic lesions who developed a gastric cancer within 2 years. The expression of the Fhit protein was always present in all preneoplastic lesions, while the Fhit protein immunostaining was distributed unevenly in 10 cases and completely lost in 6. The complete loss of Fhit expression only in areas of neoplastic low differentiation suggests that FHIT gene takes part in late gastric carcinogenesis.

Acid Anhydride Hydrolases↗

Long-term follow-up of clubfoot surgery: analysis of 44 patients.

The purpose of this study was to evaluate the long term results of clubfoot surgery. Forty-four patients were evaluated for periods from one to 41 years. The evaluation was based upon clinical, radiological and functional criteria. Results revealed that in spite of anatomically and radiologically imperfect feet, most patients demonstrated excellent levels of function. The results of other follow-up clubfoot studies were analyzed and compared to the present study.

Adolescent↗

[The role of video-laparoscopy in the management of ovarian swellings].

METHODS: Personal experience in videolaparoscopic treatment of 42 ovarian masses during the period September 1991-December 1995 is reported. Seven patients have been operated in emergency, 35 in election. Resection of the masses has been performed by two methods: dissection and electrocoagulation, generally preferred in benign functional cysts; resection by stapler (endo GIA). RESULTS: In 5 of the patients operated in emergency an hemoperitoneum was found because of the rupture of ovarian cyst; in the other two cases, respectively, a necrotic benign cyst twisted on the adnexal axis and a dermoid cyst twisted and necrotic too were found. In the 35 patients operated in election, 33 benign cysts, 1 serous cystoadenoma 1 granulosa tumour were observed. Postoperative course was always excellent, with no painful symptomatology and hospital-stay and convalescence extremely reduced (dismission from hospital approx two days after the operation). CONCLUSIONS: The different aspects which must be evaluated before choosing mini-invasive treatment are discussed. An accurate preoperative study especially by sonography and serous hormonal dosage (in particular CA 125), besides good surgical experience of the operator, are fundamental requisites in order to minimize risks of this procedure and guarantee excellent results.

Adolescent↗