Biomedical subjects

M D Gaevyĭ

Publications and source records attributed to M D Gaevyĭ.

At least 37 records · Page 2Linked to original sources

PubMed1977

[Effect of beta-adrenoreceptor blockade on cerebral circulation and extracranial vascular tone].

The influence of anapriline (propranolol) on the cerebral circulation rate, tone of the cerebral and femural vessels, pO2 in the cerebral tissue, was studied. I. v. administration of anapriline decreased the arterial blood pressure. The changes of tone of the vessels are often of the two-phase character: a decrease followed by an increase. The lowering of the arterial pressure is the most probable cause of the lowering cerebral circulation rate. pO2 decreases accordingly to the blood flow. The effect of anapriline was greater in anesthetized animals.

Anesthesia, General↗

PubMed1977

[Reactions of intra- and extracrenial vessels to noradrenaline in experimental cardiogenic shock].

Decrease in the constrictive reaction of the intra- and extracranial vessels to noradrenaline was observed in animals with cardiogenic shock; in acute experiments on anesthetized cats by resistography and rehoencephalography. Under these conditions the rise of the systemic arterial pressure under the influence of noradrenaline promoted passive dilatation of the cerebral vessels and an increase of their blood filling.

Animals↗

PubMed1977

[Method of resistography].

To eliminate the error of the resistograph connected with the animal's arterial pressure fluctuation an automatic stabilizer of the entrance pressure provided with an electromagnetic valve is proposed. To switch off the resistograph pump automatically when the blood flow into the apparatus is either hindered or stopped the following device is proposed: the pressure stabilizer and the servo system are controlled by electro-contact Hg manometers connected with the admission channel of the resistograph.

Blood Pressure Determination↗

PubMed1977

[Effect of phentolamine on cerebral circulation].

The influence of phentolamine hydrochloride on the volumentric circulation rate of the cerebral blood flow, the tone of the cerebral vessels and oxygen tension in the cerebral tissue was studied in acute experiments on anesthetized and nonanesthetized cats. Injected intravenously, phentolamine hydrochloride was found to lower the intra- and extracranial vessels for a long time, the latter to a greater extent. The circulation rate of the cerebral blood flow decreased under conditions of a significant hypotension caused by phentolamine hydrochloride and increased with a stable perfused pressure; pO2 changes in the cerebral tissue corresponded mostly to the blood flow. Preliminary atropinization of the animals and denervation of the carotid regions failed to influence the effect of phentolamine hydrochloride. The latter decreased or prevented the vasoconstrictor action of norepinephrine and phenylephrine hydrochloride (mesatone) on the cerebral vessels.

Animals↗

PubMed1975

[Effect of aminazine on cerebral circulation].

In acute experiments on anesthetized cats intravenous injection of chloromazine (2--3 mg/kg) caused a reduction in the tone of the cerebral vessels and decreased the general arterial pressure. The cerebral blood circulation increased with the stable arterial pressure or its moderate decrease. With a significant fall of arterial pressure the cerebral blood flow proved to decrease.

Animals↗

PubMed1973