PubMed Health⌕ Search

Biomedical subjects

M D Kolins

Publications and source records attributed to M D Kolins.

13 recordsLinked to original sources
PubMed1998

Lawmaking: how to be heard in Lansing and Washington.

In one way or another, government regulation affects your medical practice. Whether it is the fee schedule you receive from Medicare or a mandatory hospital stay for a new mother, decisions in Lansing and Washington, D.C. are making an impact in health care. As physicians, we are a highly valuable source of information, and therefore need to contribute our expertise to the political processes that will shape public policy for the future. Physicians must realize that without advocacy, all of our knowledge will remain untapped by our lawmakers.

Health Policy↗
PubMed1990

Informed consent, risk, and blood transfusion.

Informed consent for blood transfusion has become a necessity in light of the known risks associated with this service. All transfusion services should institute written informed consent that clearly defines the patient's options, including the use of homologous blood, autologous blood, and directed donations. The risk of transfusion with an infectious blood product is dependent on the number of donors per recipient and the prevalence of undetected, contaminated blood in the tested blood supply. The chance that an adverse transfusion will occur can be calculated by use of these variables. Comparative risks can be explained to patients, thereby providing an understanding of the transfusion risk of human immunodeficiency virus, the human T-cell leukemia virus, and the agent of non-A, non-B hepatitis (hepatitis C).

Humans↗
PubMed1988

Laboratory determination of parentage.

By incorporating basic genetic concepts and assumptions, laboratories can determine if a man is excluded from paternity or, if not excluded, determine the likelihood of paternity. The concepts of exclusion and determination of likelihood of paternity are presented.

Accreditation↗
PubMed1983

Quinine-induced thrombocytopenia following intravenous use of heroin.

Profound thrombocytopenia developed in a 22-year-old man after intravenous use of heroin. A high-titer, quinine-dependent, platelet-specific antibody was detected in his serum using lysis of normal platelets labeled with chromium 51 and an electroimmunoassay for measurement of platelet-associated IgG. The antibody was specific for quinine and failed to react with platelets in the presence of quinidine hydrochloride or two structural analogues of heroin. Quinine, a common adulterant found in heroin, was detected in the patient's blood and urine. On the basis of these observations, the patient was judged to have quinine-induced immunologic thrombocytopenia. To our knowledge, this report is the first to confirm that quinine used as an adulterant can induce immunologic thrombocytopenia following an injection of heroin.

Adult↗
PubMed1980

Amniotic fluid phospholipids measured by continuous-development thin-layer chromatography.

We describe a one-dimensional thin-layer chromatographic system for separation of amniotic fluid phosphatidylcholine, sphingomyelin, phosphatidylglycerol, phosphatidylinositol, phosphatidylserine, and phosphatidylethanolamine in amniotic fluid. We utilize short-bed continuous development and "high performance" thin-layer chromatography. Phospholipids are detected with an antimony molybdate staining reagent and quantitated by transmittance densitometry. This system is more sensitive to changes in lecithin/sphingomyelin ratios than are planimetric evaluations.

Amniotic Fluid↗
PubMedDate not supplied

Diagnosis of pancreatic lesions by percutaneous aspiration biopsy.

Fifteen patients suspected of having pancreatic disease were studied by transabdominal percutaneous fine needle aspiration biopsy guided by computed tomography. Ten patients had aspirates positive for carcinoma: seven had clinically advanced disease, and the diagnostic procedure spared them laparotomy; two patients underwent laparotomy for choledochoduodenostomy; and one underwent exploratory laparotomy resulting in pancreatoduodenectomy. Four aspirates were negative for malignancy, but one patient was found ultimately to have carcinoma. One specimen was unsatisfactory. We conclude that transabdominal percutaneous fine needle aspiration cytology is a safe and simple procedure for distinguishing benign from malignant lesions. There were no complications from the procedure. We experienced no false positives and one false negative.

Aged↗