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Biomedical subjects

M Florescu

Publications and source records attributed to M Florescu.

48 records · Page 3Linked to original sources
PubMedDate not supplied

Histopathologic aspects in endometrium dysplasias.

The paper presents a study consisting of 87 cases of endometrial hyperplasias. Histopathologic examination allowed us to identify the singular glandulo-cystic and adenomatous hyperplasia and the coexistence of the two lesions, but also the association (for two cases) of chronic adenomatous hyperplasia to endometrial carcinoma. These aspects plead for considering hyperplasia as a precancerous lesion taking into account the physiological stage when it appears.

Endometrial Hyperplasia↗
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[Plastic repair with Plastex-type synthetic mesh in abdominal wall defects].

This paper analyses a statistical series of 53 patients suffering from single or multiple abdominal wall defects and who were managed by plastic surgery with Plastex type synthetic mesh. Our results are pleading for the extension of the indications of Plastex mesh buttressing surgery beyond the usual recurrent "hernia" cases to the patients admitted with nonrecurrent either large abdominal wall defects or, and poor-quality musculoaponevrotic parietes of the abdominal wall. Our study recorded recurrence and postoperative morbidity rates have been minimal due to both a correct selection of cases for this type of surgical repair and an adequate patient preoperative management in which antibiotic and thromboembolic prophylaxis have been applied on a regular basis.

Abdominal Muscles↗
PubMedDate not supplied

Pseudoepithelimatous hyperplasia positive and differential diagnosis.

Our study intended to describe some inflammatory and tumoral lesions associated to pseudoepithelimatous hyperplasia. In our casuistry, pseudoepithelimatous hyperplasia was determined by tuberculosis in two cases, granulomatous ulcerate epuils in 4 cases, myoblastoma in one case. Recognising these lesions is very important, since it helps differentiating between these tumors and some epidermal carcinomas, the two affections involving different therapies.

Adult↗
PubMedDate not supplied

Remarks on some cases of stromal hyperplasia and endometrial sarcoma.

Our study works out different aspects which can appear both in stomal hyperplasias and endometrial sarcoma. It is possible to recognise histopathologic varieties of the stromal hyperplasias by a close co-operation with the gynaecologist. The necessity of a right diagnosis for all the forms of stromal hyperplasia spreads from the significance of precancerous lesion of some of them. We also mention the difficulties of diagnosis risen by stromal hyperplasias and endometrial sarcoma and also the necessity of a certain diagnosis having into consideration the prognostic and the different therapy imposed by the two diseases.

Adult↗
PubMedDate not supplied

[Nosocomial infections in the Clinica Chirurgie CFR, Craiova].

The authors present Craiova CFR General Surgery Clinic experience on hospital infections from 1991 through 1996. This study shows that the frequency of hospital infections in our clinic is greater than all the other postoperative complications. Over the investigated period of time we witnessed an increase in the incidence of the postoperative septic complications in addition to those directly linked to the operated interventions (e.g. wound infections, postoperative peritonitis) such as: pulmonary infections: urinary tract infections, catheter sepsis etc. Finally, the authors pointed to the consequences of the hospital infections such as: mortality and late morbidity rates, economic implications. Thus, it is worth mentioning that 30 deaths (75%) out of our clinic total of 40 over the studied period of time were due to a postoperative infections and treatments.

Cross Infection↗
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Histopathologic and immunohistochemic correlations in virus B chronic hepatitis.

Complete diagnosis of chronic hepatitis relies on exploring the liver by bipsic punction, performing the classic histopathologic and immunohistochemic exams. We worked out viral antigens hepatocytes by using avidin-biotin-peroxidase complex technique as following: Ag HBs placed in cytoplasm or at the level of the cell membrane. Ag HBc preferably placed in nucleus and, a small part of it, in cytoplasm. Ag HD present especially in nucleus. A correlation between tissular antigen expression and hepatic histopathologic aspect was established. Two main types of viral expression were remarked: a regressive type reflected by cytoplasmatic Ag HBs in the absence of generalised nuclear Ag HBc--situations linked to persistent chronic hepatitis: an aggressive type characterised by the presence of the focal nuclear Ag HBc, cytoplasmatic Ag HBc or antigen HD--situations linked to active chronic hepatitis with various degrees of severity.

Biopsy, Needle↗
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Microscopic and ultrastructural aspects in retinoblastoma.

A number of 12 retinoblastoma cases were studied. We had in view a number of histopathological aspects (tumor type, neighbouring structures invasion) which are considered to be decisive in appreciating the vital prognosis. We mention that undifferential retinoblastoma of histopathological type was met in 8 cases and the neighbouring structures invasion was present in 7 of them. We also studied the ultrastructura of the tumor cells belonging to the malignant tumor.

Eye Neoplasms↗
PubMedDate not supplied

Considerations on endometrial epithelial metaplasia.

Our study aimed to the various histopathological aspects of the endometrial epithelial metaplasia and the endometrial lesions which appear more frequently associated to these changes. Being considered as isolated, endometrial epithelial metaplasia has no prognostic relevance. It is important that the histopathologist recognize it, because its association to some benign lesions (especially to the endometrial glandular hyperplasia) may generate confusion with carcinoma.

Curettage↗
PubMedDate not supplied

[A plea for the conservative treatment of breast cancer].

This article is a plea for the implementation of early-stage breast cancer conservative therapy into as many surgical clinics as possible. The aforementioned statement relies mainly on published papers and data (the protocol included) provided to us by Instituti Clinici di Perfezionamento di Milano experts in breast cancer conservative therapy and to a lesser extent on our not too numerous results (30 cases) obtained over the past 2 years since we applied the Milano protocol on a regular basis. Thus we support the view that the breast-conserving treatment is suitable for clinical stage I or II carcinoma whose tumors are 3 cm or less in greatest diameter, provided axillary lymphadenectomy is associated for prognostic and future management guidance reasons, but not for cure. Breast-limited postoperative radiation treatment is foremost aimed at local recurrences rate reduction without significantly influencing survival rate. Postoperative chemotherapy, indicated for node-positive patients and/or primary tumors over 1 cm in greatest, diameter, has been proved to contribute to long-term survival rate. However, both the small sample size and the short period of observation of our study prevented us from drawing firm conclusions directly.

Adenocarcinoma↗
PubMedDate not supplied

[Urinary infections with hospital germs in general surgery].

Nosocomial urinary tract infection is the most common type of sepsis in the post-surgical patient. This paper presents our experience with 218 nosocomial urinary infections (34.93% of our postoperative infections) which complicated the postoperative course of 1002 (21.75%) urethral catheterized patients out of a total of 5950 (3.6%) operated on and under study individuals. Thus we found that urethral catheterization is the most important risk factor for post-surgery urinary infections. Moreover, in our series the postoperative urinary tract sepsis bacteriology is dominated (> 95% of cases) by aerobic gram-negative bacilli that mainly reside in the bowel and also commonly colonize the perineum. Furthermore, we demonstrated that post-surgical urinary infections did not influence directly death rate but they had a significant bearing on care costs. Finally we consider the prevention of postoperative nosocomial urinary tract sepsis as an essential principle of this condition management.

Cross Infection↗