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Biomedical subjects

M Günther

Publications and source records attributed to M Günther.

At least 91 records · Page 5Linked to original sources
PubMed1979

[A contribution to bladder amyloidosis].

It is reported on a localised primary amyolidosis of the urinary bladder with a progressing course. In contrast to the prevailing observations of other authors during two years an increasing bilateral urinary stasis developed so that finally after an at first unilateral nephrostomy due to an infected retention kidney the bilateral ureter-intestine-anastomosis became necessary. Apart from a short description of the amyloidosis from the general and especially urologi-al point of view it is particularly referred to diagnostic difficulties, since the various forms of amyloidosis have a different prognosis and demand a therapy.

Amyloidosis↗
PubMed1979

[DNFB reaction in bladder cancer, an immunological study].

It is stated that the determination of the reactivity against the primary antigen dinitrofluorbenzol by means of the epicutaneous skin test before the beginning of a therapy may give an essential reference to the spreading of the tumour and to the prognosis. The course control in patients with carcinoma of the urinary bladder should therefore consist not only of clinical but also of immunological examinations.

Aged↗
PubMed1979

[Organ preservation in intra- and extracorporeal kidney surgery].

With the help of cases of own patients is reported on the possibility of organ preservation in intra- and extracorporal renal surgery. In 5 patients with tumours, 3 patients with coral calculi and one patient with an extended disease of the ureter five times the extracorporal renal surgery with following autotransplantation and initial pulsatile fall stream perfusion was performed. Four times the in-situ-perfusion with hypothermic Collins solution and in-situ-operation was performed. Indication and advantages for the different methods are demarcated.

Adenocarcinoma↗
PubMed1979

[Ultrasonographic differential diagnosis of imminent abortion (author's transl)].

Two-hundred patients, hospitalised for imminent abortion in the sixth to 16th weeks of pregnancy, underwent 294 ultrasonic compound B scans. Gravidity was found to be intact in 68 per cent of all cases, but 13.6 per cent of these ended in abortion prior to the 28th week of pregnancy. Four hydatiform moles and 17 missed abortions were reliably diagnosed. Ultrasonography, even without grey-scale equipment, may be of greatest usefulness for differential diagnosis between intact early pregnancy, missed abortion, blighted ovum, and hydatiform mole, when used by an experienced specialist in close cooperation with the clinical practitioner.

Abortion, Missed↗
PubMed1978

A contribution to immunological tumour diagnostics in urology.

Fifty-four patients with malignant and other diseases of the urinary bladder and the prostate were examined for lymphocyte sensitization by means of electrophoretic mobility test (EM test). In this antigens from brain tissue (EF) and from malignomas of kidney, urinary bladder and prostate were used. Positive HEP values were obtained in 40 patients out of 42 with malignant tumours and in 5 patients out of 12 with other kidney diseases. With the corresponding tumour-associated antigens (TAA) in the EM-test, the histological tumour diagnosis could be confirmed in every case. Positive findings after using EF as well as the corresponding TAA are with great probability an indication of a malignant disease.

Adenocarcinoma↗
PubMed1978

[Lymphocyte transformation test with streptococcal antigens in newborn infants and their mothers].

Following streptococcal mitogens and antigens were tested in the lymphocyte transformation test with human cord blood and maternal blood: streptococcal M1- and M19-proteins, mucopeptide, erythrogenic toxins and additional phytohemagglutinin. There are no significant differences in the blastogenic response with the different mitogens and antigens in maternal and cord blood. The cord blood lymphocytes show the same degree of blastogenic reaction to the mitogens and antigens as the maternal lymphocytes, that may reflect the state of readiness for cellular immunological defence. The spontaneous incorporation of 3H-labelled thymidine into cord blood lymphoblasts is significant higher than in lymphoblasts of maternal blood.--The results of specific and unspecific stimulation by means of steptococcal antigens are discussed.

Adult↗
PubMed1978

[Perfusion technic during clinical intra- and extracorporeal tumor removal from a solitary kidney].

On the basis of own experiences in operations of tumour-carrying kidneys two perfusion techniques for the intra- or extracorporal renal surgery are exolained and weighed one to another. In the in-situ-perfusion the pulsatile mechanical perfusion with supervisable flow, perfusate pressure and under direct measuring of temperature on organs has proved. The disadvantage of the in-situ-perfusion in contrast to the extra-corporal surgery consists in the impossibility of the local after irradiation.

Humans↗
PubMed1978

[The clinical picture and pathology of benign tumors of the female urethra].

Benign neoplasia of urethra are of frequent by aged women. Epithelial tumours (polyps, papilloms) are distinguished from mesenchymal tumours (fibroms, myoms, angioms) histologically. Dislocations of the mucosa and real malignoms of the urethra are marked off from these. The authors report about the rarity of mesenchymal neoplasia and represent a case by which it comes to retention of urine because of a big leiomyoma. Diagnosis and therapy are described in detail.

Adult↗
PubMed1978

[Course of cellular immunity in urologic neoplasms].

Apart from a purely qualitative evidence concerning the presence of a specific sensibilisation it is possible to estimate also its strength or the blocking factors appearing in the serum of tumour carriers by means of the electrophoresis mobility test. By this it seems to be possible to make an evidence concerning the immunological reaction position of the tumour patient with the possibility to make conclusions as to the prognosis of the patient.

Antigens, Neoplasm↗
PubMed1978

[A contribution to the early diagnosis and differential diagnosis of bladder neoplasms by means of immunological methods].

According to the present examinations it is pretty probable that already in early histological forms of the carcinoma of the urinary bladder the EM-test is able to indicate immunologically malignity, i.e. that the papillary non-infiltrating carcinoma of the transitional cell as well as the carcinoma in situ of the urinary bladder (23) also immunologically behave like tumors of the bladder. In differential-diagnostic questions concerning the organ localisation of the primary tumor the EM-test seems to give valuable references. Histologically not unequivocally malignant tumors of the bladder with positive results in the EM-test should be submitted to an exacter examination and control.

Adult↗
PubMed1977

[Esophageal varices hemorrhage in portal hypertension (author's transl)].

Diagnostic and therapeutic possibilities for esophageal varices hemorrhage in portal hypertension are indicated with reference to 149 patients. In the acute phase, operative measures are to be rejected because the lethality is too high. Conservative treatment with a Blakemore-Sengstaken probe should always be introduced at first. After confirmation of the conditions in the liver, a pressure-reducing anastomosis operation (delayed emergency shunt) must be performed. For this purpose we prefer the terminolateral splenorenal anastomosis.

Adult↗
PubMed1977

[Immunodiagnosis of urologic tumors].

In 42 patients with malignant and benign diseases of the kidney, the urinary bladder and the prostate the sensitization of the lymphocytes was investigated in the cell electrophoresis mobility test. In these cases human encephalitogenic protein and tumour-associated antigens from malignomas of kidney, urinary bladder and prostate were used as antigen. When using human encephalitogenic protein 3 "falsely positive" and 2 "falsely negative" results were got, whereas, when using the corresponding tumour-associated antigens in the cell electrophoresis mobility test in every case the histologically ascertained tumour diagnosis could be confirmed.

Adenocarcinoma↗
PubMed1977

[Role of B streptococci in perinatal medicine].

Vaginal swabs from 1140 women were investigated for presence of group B-streptococci. In nonpregnant women the carriage rate was 3.3%. During the pregnancy the highest colonisation rate was in the second trimenon. The serotypes were distributed approxmiately the same in both groups of patients, with the exception of types III and R. All strains were sensitive against ampicillin and lincomycin, in 6 cases we found a reduced sensitivity against penicillin. These results are compared with those from other authors and discussed in regard to sepsis and meningitis of the newborn.

Anti-Bacterial Agents↗
PubMed1976

[Urolithiasis and its conservative treatment based on analysis of the calculi].

The exact analysis of urinary calculi is the condition for an aimed conservative therapy of urolithiasis. As standardized method of the analysis of urinary calculi the X-ray diffraction was introduced in the GDR. This investigation method allows a qualitative and quantitative analysis of the concrements. The possibilities of the conservative therapy of urolithiasis were explained. To this conservative treatment belong the treatment of a colic, the removal of a calculus, the litholysis and the prophylaxis of recidivations.

Colic↗