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Biomedical subjects

M K Thompson

Publications and source records attributed to M K Thompson.

At least 37 records · Page 2Linked to original sources

Human immune response to iron-repressible outer membrane proteins of Neisseria meningitidis.

Neisseria meningitidis grown under iron-limiting conditions in vitro expresses additional iron-repressible outer membrane proteins (FeRPs). To see which FeRPs were expressed and immunogenic in human infection, we examined purified membranes from four meningococcal disease isolates with Western blotting of patient sera. Convalescent serum from each patient contained immunoglobulin G (IgG) and IgM antibodies against the homologous 70-kilodalton (kDa) FeRP and IgG antibody to the homologous 94-kDa FeRPs. Three other immunoreactive FeRPs were identified in two or more strains. Neither acute-phase sera nor pooled normal human sera contained appreciable levels of these antibodies. Antigenic cross-reactivity among FeRPs was suggested by the observation that the convalescent sera of two patients contained IgG antibodies reactive with the 70- and 94-kDa FeRPs and IgM antibodies reactive with the 70-kDa FeRPs from all four strains. Additionally, rabbit antiserum against the 70-kDa FeRP from one of these disease isolates contained IgG and IgM antibodies that reacted in Western blots with the 70-kDa FeRPs in all four strains. These results demonstrate that meningococcal FeRPs are expressed and immunogenic in vivo and that certain of these proteins are immunologically cross-reactive.

Antibodies, Bacterial↗

Health care in the Soviet Union.

More nurses today have the opportunity to visit other countries and broaden their ideas of health care and nursing. Several colleagues and I have prepared a series of three articles that describe visits to the Soviet Union, China and Africa by nurses participating in exchange tours conducted by Professional Seminar Consultants of Albuquerque, New Mexico. During these two-week trips, American nurses were able to observe health care facilities and talk to health care providers in other countries. Although short visits such as these are not able to provide in-depth understanding of the health care systems or cultures involved, they have provided provocative ideas about how our own health care system differs from others. In some instances, our health care system seems the better one, but in many instances we were able to gain insights from our observations that may help us improve our own system of nursing and health care. This is the first in a series of three articles reporting professional exchange tours between American nurses and nurses of other countries. In this article, the health care system of the Soviet Union is discussed and compared to the United States' system of health care. From this comparison come several insights into ways for improving health care delivery.

Attitude to Health↗

Family development theory.

This is the first in a series of columns which will discuss theories " borrowed " from other disciplines and used in clinical practice. In this article, Duvall and Terkleson 's theories of family development are examined for their clinical usefulness. Examples of their utility and limitations are included. Suggestions for ways in which clinical practice may direct further nursing research are suggested.

Family↗

Anorexia nervosa.

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Anorexia Nervosa↗

A good home.

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Aged↗