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Biomedical subjects

M Litschgi

Publications and source records attributed to M Litschgi.

At least 55 records · Page 3Linked to original sources

[Blood glucose in the full-term newborn infant in the 1st hour following birth].

Blood glucose (BG) concentrations were measured in cordblood and in capillary blood 15 and 60 min after birth in 672 consecutive full term newborns with adequate birth weight and without major perinatal complications. The glucose oxydase method was used. The results (mean +/- 1 SD) were in umbilical vein 67.6 +/- 20.1 mg%, in umbilical artery 60.3 +/- 20.0 mg%, 15 min after delivery 49.4 +/- 20.5 mg%, and 60 min after delivery 47.5 +/- 17.4 mg%. In 29% of the babies umbilical artery BG was below 50 mg%. 12% showed a "hypoglycemia" below 30 mg% (1.7 mmol/l) after 15 min, 17.5% after 15 and/or after 60 min. Newborns with arterial cord BG below 50 mg% turned out to be hypoglycemic after 15 min three times more often than newborns with arterial cord BG above 50 mg%. Hypoglycemic babies at age of 15 min showed 60-min-BG-values of 40.4 +/- 13.0 mg% when they had received a 10% glucose feed (20-30 ml) at the age of 1/2 h, compared with 31.1 +/- 7.0 mg% without such a supplement. Although this "early hypoglycemia" was asymptomatic in nearly all our newborns, we tend to consider it as a serious risk factor for the occurrence of a potentially dangerous symptomatic neonatal hypoglycemia.

Blood Glucose↗

[Diagnostic criteria of neonatal acidosis during the first 60 minutes postpartum].

Normal deliveries (without intra-partum warning signs or symptoms of neonatal asphyxia) were selected to form a normal population of newborns from which normal values were calculated for the pH of umbilical artery and heel prick blood at birth and 15, 30 and 60 minutes after delivery. The following lower limits were found: (formula: see text) These limits were checked for usefulness in a random population. In the light of this information the Swiss Group for Neonatology has redefined the terms "intrapartum warning signs" and "neonatal asphyxia".

Acidosis↗

[Course of twin pregnancies after foetal death in utero (author's transl)].

Premature foetal death in utero of a twin with continued pregnancy and birth after a lapse of at least 12 hours, is a relatively rare occurrence. This was recorded at the University Gynecological Clinic in Basel in 13 women within the last nine and a half years, representing a frequency rate of 0.07% in relation to the total number of births, or 6.8% of all twin births. The special circumstances governing these cases are described and compared with reports published in medical literature on similar cases.

Female↗

[Comments on cerclage (author's transl)].

Cerclage was performed by us during the past 5 1/2 years in 71 women (0.68% of all births). In 23 women, cerclage was performed prophylactically and in 48 women as therapy of early maturing of the cervix. Cerclage was applied, mainly according to McDonald, between the 13th and 33rd weeks of pregnancy, maximum incidence of surgery occurring between the 17th and 27th week (63%). Cervical insufficiency is only temporarily removed by cerclage. After the suture has been removed, cervical dilatation should be variable. If this is not the case, the diagnosis of "cervical insufficiency" must be considered doubtful. This criterion was fulfilled in 83% of the therapeutic cases of cerclage compared with 43% in the prophylactic cases. Within 24 hours after removal of this suture, 39 patients (59%) had given birth. The prophylactically indicated cerclages often did not meet the criterion cervical dilatation uteri after removal of suture and rapid birth", whereas the majority of the therapeutic cerclages complied with the criterion. Our results are compared with those published in the literature. Despite the trend noticeable in literature towards a more liberal indication of cerclage, we will continue to perform this operation with discretion.

Abortion, Spontaneous↗

[A case of superfetation (author's transl)].

A case of superfetation is reported. A 23 year old gravida 3, para 1, aborta 1 had a D & C and partial left salpingectomy for ruptured left tubal pregnancy. The microscopic examination of the curettings and the left fallopian tube revealed two pregnancies. The tubal pregnancy was obviously older than the intra-uterine pregnancy and the two fertilized eggs had to result from different ovulations.

Adult↗

[Single vaginal vault recurrences following endometrial carcinoma stage 1 treated by operation (author's transl)].

From 1950--1975 201 women had total abdominal hysterectomies and bilateral salpingoophorectomies for stage 1 carcinoma of the endometrium, out of a total of 280 endometrial carcinomas. All patients had post-operative external radiation. A prophylactic vaginal radium insertion was not done. Of 191 follow-up cases from between 2 and 10 years following the operation 2 patients had recurrences of the vaginal vault and 2 patients had single vaginal metastases. Based on a study of the literature and the personal results, it is suggested that a prophylactic vaginal radium insertion is justified only in cases of undifferentiated endometrial carcinomas stage 1 group I type G3 with 50% or more tumour invasion of the myometrium.

Adult↗

[Prediction of anemia or polycytosis from the hematocrit determination in the umbilical artery of the newborn (author's transl)].

Among 430 deliveries a random group of 100 newborns were used to determine the value of the umbilical arterial hematocrit for the prediction of neonatal anemia or polycytosis. Normal values were Hct, 48 vol.% to 72%. Even considering the PH of umbilical arterial blood, the Hct. in the umbilical attery permits an excellent prediction on the neonatal Hct. at 15 to 60 minutes post-partum. When the umbilical arterial Hct. is normal a capillary Hct. determination is not necessary for routine diagnosis. If the umbilical arterial Hct. is below 46% or above 61% a capillary Hct. is necessary since below 46% or above 61% neonatal anemia or polycytosis could be found.

Anemia, Neonatal↗

[The forensic value of the length and weight of newborns, the placental weight and the correlation between placental and newborn weight in the evaluation of paternity (author's transl)].

The length of the infant, the weight of the infant, the weight of the placenta, and the correlation between the weight of the placenta and the weight of the infant are coarse parameters for the estimation of the maturity of an infant. We plotted these parameters of 20,000 deliveries in relationship to the stated length of gestation from 23--46 weeks. Our results correspond to those quoted in the literature. The values of the parameters show a marked variation which is accentuated by the small number of cases with very short or very prolonged gestation. These parameters are only of limited value in the determination of the paternity. The mean values including the first standard deviations are of some importance.

Birth Weight↗

[Possible late complications after peridural anaesthesia (author's transl)].

140 women who had received peridural anaesthesia (PDA) during childbirth at the University Gynaecological Hospital, Basel, in 1977, were retrospectively questioned on the occurrence of backache and headache during the puerperium subsequent to peridural anaesthesia. The "matched pairs" technique was employed for the controls. The inquiry revealed that in the PDA group 69 women (49%) and in the control group 39 women (28%) complained of increased backache during the puerperium. For 30 patients (44%) the complaints were a frequently disturbing factor in their everyday work. In the control group, this was true of 11 women (28%). 46 patients (33%) of the PDA group complained of increased headache during the puerperium, against 16 patients (11%) of the control group. 22 women (49%) of the PDA group felt disturbed in their daily work against 4 women (25%) among the controls. The findings are compared with data in literature, and the aetiology of the symptoms is discussed.

Anesthesia, Epidural↗

[Primary dysmenorrhoea and hyperprolactinemia (author's transl)].

Between 5 and 10% of all young girls and women suffer of severe primary dysmenorrhoea which interfers monthly with their activities. In this type of primary dysmenorrhoea we found hyperprolactinemia in 13 of 15 women who were examined. All 15 patients had a pituitary tumour ruled out and were treated with Bromo-ergocryptine (parlodel). Eight patients became free of symptoms and five were well improved. The possible correlation of hyperprolactinemia to premenstrual tension and severe primary dysmenorrhoea is discussed.

Adolescent↗

[Reduction of the incidence of postoperative morbidity after vaginal operations by the choice of suture material (author's transl)].

Dexon suture material is capable of lowering the postoperative morbidity. Among 142 vaginal operations for prolapse 82 were done with catgut and 60 with Dexon. In the catgut group 24.4% had a temperature of 37.5 or higher for more than one day and 15.0% in the Dexon group. Secondary vaginal bleeding occurred in 15.8% of the catgut patients and in 6.6% of the Dexon patients. The mean hospital stay was 18.8 days after operations with catgut and 14.6 days after operations with Dexon. There were less wound dehiscences than in the group operated with catgut. Dexon has higher tensile strength than catgut. It is absorbed by hydrolysis and causes less tissue reaction. Dexon shows the desirable properties of both an absorable and a nonabsorbable suture material.

Female↗