[The influence of the EPH Gestosis on the duration of pregnancy (author's transl)].
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Biomedical subjects
Publications and source records attributed to M Litschgi.
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During the past nine years 70 enteroceles were observed. There were 27 primary and 43 secondary enteroceles. Etiologic factors were multiparity, advanced age, general lack of elasticity, obestiy, constipation and increased intra-abdominal pressure. The pathogenesis of primary enteroceles was usually to do a genital prolapse, tissue atrophy, a distended pouch of Douglas due to a tumour. The pathogenesis of secondary enterocele following previous uterine surgery was that at times the pre-existent enterocele had not been observed and the space between the uterosacral ligament and the rectum not been closed, or the patients had vaginal hysterectomies and anterior and posterior colporrhaphies, or the patients had previous uterine suspensions or abdominal hysterectomies. The interval between uterine surgery and enterocele was a mean 1.5 years for vaginal hysterectomies and a mean 15 years for the other operations. Different operative procedures for enterocele are discussed. In 90% of the cases the enteroceles were repaired vaginally by the method of Shaw O'Sullivan.
The diagnostic and therapeutic problems connected with beta-thalassaemia minor during pregnancy are demonstrated by describing the cases of 26 women hospitalised during a total of 38 deliveries in the authors' clinic. All patients came from the Mediterranean area and showed the disease pattern of beta-thalassaemia minor both in the erythrocyte count and in haemoglobin electrophoresis. This aenemia, which is rather rare, reamined largely constant, with few exceptions. Iron substitution during pregnancy was effected only if an iron deficiency was found, the iron level in the serum being subjected to repeated control examinations. These risk pregnancies were controlled by CT scanning, mainly to detect any possible foetal hypoxia caused by aenemia. There was no increased incidence of deformities of the newborn, nor of premature births. However, there was a slight increase of the mean placental weight. This hypertrophy was probably the manifestation of a compensation mechanism. The proportion of slightly depressed newborn was also increased. The importance of examining the partner as well, is emphasised.
In addition to those children delivered by cesarean, a noticeable number of premature infants show a neonatal depression without intrauterine or neonatal acidosis. The reasons for this are only partially known. Anesthesia, on the one hand, and the underdeveloped brain, on the other hand, are held responsible. The prognosis of these children is relatively serious. On the one hand, they show a frequent incidence of neurologic disorders, or an increased rate of deformity on the other which although without immediate intrauterine consequences, will render extrauterine life substantially more difficult, if not impossible.
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Casuistic contribution of a sucessfully with Gestagen treated stage IV corpus carcinoma which previously had been operated and undergone radiotherapy. Ten years after the primary treatment the patient presented herself asymptomatic and clinically free of a tumor. The possible mechanism of the effect of the Gestagen-therapy is discussed as well as the indication for the administration of Gestagen in a corpus carcinoma.
Pelvic venous thrombosis during pregnancy is a rare event. The treatment discussed in the literature consists mostly of recommendations for therapeutic fibrinolysis. The surgical alternative is the retrograde operative thrombectomy with concommitant Caesarean Section. Two cases were successfully treated by this method at 33 and 39 weeks gestation. The cases are reported. The operative technique is described. The advantages and disadvantages of this treatment are discussed.
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The culture is the optimal procedure for the diagnosis of gonorrhea in the female and should be used in every suspicious case. The percentage of loss through use of a transport medium (Stuart) and by submitting the specimen to a central laboratory for examination affects the results. For this reason a simple procedure was tested based on Chapin's candle-flame method and using Martin and Thayer's selective culture medium. This method can be used in every laboratory. The described procedure requires little more work than Gram's method. In our test series, a higher percentage of positive results were obtained with this method than with the microscopic diagnosis and the transport medium.
Epimestrol 5 mg. daily for 10 days was administered in 119 treatment cycles to 21 women with normal gonadotropins and 33 ovulations were induced. Of the 21 patients, 7 had secondary amenorrhea, 10 had anovulatory oligomenorrhea and 4 had ovulatory oligomenorrhea. 17 patients desired pregnancies and 6 became pregnant. There was 1 pregnancy among 5 women with secondary amenorrhea. There were 3 pregnancies among 9 patients with anovulatory oligomenorrhea and 2 pregnancies in 3 patients with ovulatory oligomenorrhea. The pregnancy rate was 35%. Side effects were not observed.
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