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Biomedical subjects

M M Seredenko

Publications and source records attributed to M M Seredenko.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

[Serum acid phosphatase activity in rats with hypoxia of different etiologies].

Experiments on male rats have shown that the acid phosphatase activity increases in all the types of hypoxia (circulatory-hemic, hemic and hypoxic), in blood serum. An increase in the activity of this enzyme distinctly correlates with hypoxia gravity. A supposition is advanced that the blood enzyme level of lysosomal hydrolases can reflect the functional state of the lysosomal apparatus in cells of the organism.

Acid Phosphatase↗
PubMedDate not supplied

[Effect of ionol on the activity of oxidative enzymes and ultrastructure of myocardial hematoparenchymatous barrier in hypoxic hypoxia].

Experiments were conducted on 112 adult male Wistar rats to study the effect of preliminary ionol administration on the activity of oxidation enzymes and ultrastructure of the hematoparenchymatous barrier (HPB) in the myocardium in acute and prolonged hypoxic hypoxia. It is shown that ionol was conducive to minimal damage of HPB ultrastructures in hypoxia and had a positive effect on oxidation metabolism of the myocardium: removed inhibition of isocitrate and malate dehydrogenase, activated the key enzymes of transport of reduction equivalents in the mitochondria.

Animals↗
PubMedDate not supplied

[The effect of inert gases on the intensity of lipid peroxidation in the rat liver].

The presence of helium and argon in gas mixtures increases the peroxidation rate of lipids in homogenates and has no influence on this index in the mitochondrial and microsomal fractions of the rat liver. An assumption is advanced that the realization of effects of the inactive gases in question is realized via the plasma membranes of cells.

Animals↗
PubMedDate not supplied

[Disorders of external respiration and oxygen transport and utilization in stress].

A specific hypoxic condition characterized by a combination of signs of hypoxic, circulatory, and primary tissue hypoxia develops in rats after 6-hour immobilization stress. Post-stress hypoxia is accompanied with accumulation of lactate, decompensated metabolic acidosis, and activation of lipid peroxidation processes in the blood and tissues. Besides, a complex of changes of external respiration, its regulation and biomechanics, inhibition of pulmonary gas exchange is encountered after the stress, which is linked with the development of specific stress damage to the lungs which can be characterized as the stress lung syndrome.

Acidosis↗