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Biomedical subjects

M Maillet

Publications and source records attributed to M Maillet.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Reduction of bleeding during microsurgery of the middle ear by amiodarone].

Operative bleeding was reduced in 47 patients undergoing middle ear microsurgery by means of an intravenous infusion of Amiodarone. Total doses of the order of 1 mg.kg-1 were remarkably effective without adverse effects. This result is attributed to the capacity of Amiodarone to reduce the increase in blood pressure and particularly the tachycardia induced by release of endogenous (operative stress) and exogenous (local adrenaline infiltrations) catecholamines.

Adolescent↗
PubMed1983

[Effect of collagenase, hyaluronidase and pronase, alone or combined with cationic markers, on the renal filtration barrier in the rat].

The authors investigate the effect of collagenase, hyaluronidase and pronase, used either alone or associated with cationic tracers such as Alcian Blue, Ruth enium Red and Polyethyleneimine on the Rat glomerular filtration barrier. Collagenase appears to promote the perviousness of the three constitutive layers of the glomerular basement membrane. The effects of hyaluronidase and pronase seem to be specific and permit to suppose that the glomerular basement membrane supports several types of anionic sites. The affinity of cationic tracers seems to fluctuate according to the constitution of these sites.

Alcian Blue↗
PubMed1982

Maternal and fetal concentration of morphine after intrathecal administration during labour.

Twenty-five healthy women in labour received morphine 1-1.75 mg in normal saline intrathecally. The residual pain was evaluated on a scale from 0 to 5 at 10 min (score 2.5) and at 25 min (score 1.5). After delivery the maternal and fetal plasma morphine concentrations were measured by radioimmunoassay in 14 parturients. Twenty-three women of 25 had vaginal deliveries, 20 of them without forceps. The maternal and fetal plasma concentrations of morphine were 6 ng ml-1 or less. The intrathecal (but not extradural) administration of morphine is effective and could provide an interesting alternative for pain relief in labour.

Anesthesia, Obstetrical↗
PubMed1982

[Morphine analgesia by the intrathecal route].

30 patients for whom an epidural injection using local anaesthesia was hazardous (deformed spine) or contra-indicated (allergic to local anaesthetic agents) received an injection of 0.008 mg cm-1 of morphine chlorhydrate intrathecally. Residual pain scored from 0 to 5 was 2.5 after 10 minutes and 1.5 after 25 minutes. Thereafter there was only a simple ache which was well tolerated right up to the time of delivery. Uterine action was not changed, which allowed 27 labours to be completed vaginally, of which 23 were without forceps. There was no haemodynamic change or respiratory depression, either immediately of later, in the mother nor in the infant (there were 26 Apgar scores of 9 or more). The ratio of plasma concentrations of morphine between the mother and the fetus using radio-immunological assays was inverted as time passed. These were at 6 mg ml-1 or less, which explains the medullary characteristic of the analgesia and the absence of general repercussions. The safety that is offered by the poor diffusion of substance between the fetus and the mother and the ability to prevent secondary effects (pruritus and headache) are features that make intrathecal analgesia and interesting alternative to a conduction block in labour.

Anesthesia, Obstetrical↗
PubMed1976

[Urinary cytology in adult men].

Urinary cytology is a good test for estimation of woman's hormonal situation. In a previous paper, the authors showed an "estrogenic" like effect of digitalin, in urocytograms of post-menopausical women. In the present report, the urocytograms of 139 men, 17 to 84 years old, without any urinary disease and treated or not by digitalin, are studied. Normal urinary cytology in the adult and its modifications under digitalin treatment are shown.

Adolescent↗