[Preoperative hemosorption and immunocorrection in mechanical jaundice patients].
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Biomedical subjects
Publications and source records attributed to M N Molodenkov.
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Measurements of chemiluminescence of apo-B-containing lipoproteins of blood serum enables one to evaluate their capability of peroxidation in the presence of ferrous ions. The recording of chemiluminescence changes in the standard chemiluminescent system in the presence of ferrous ions after adding the supernatant remained after the precipitation of apo-B-containing lipoproteins may serve a simple test for the assessment of blood serum antioxidant activity.
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Specific protein, thermostable alpha-globulin, was found with the use of immunochemical analysis in carbon eluents after hemosorption in patients with autoimmune diseases. It is suggested that positive clinical effect of hemosorption might be determined by sorption of thermostable alpha-globulin from the patients' blood.
The rabbits fed cholesterol show significant changes in lipid metabolism and develop hypercholesterolemia that indicate that development of experimental atherosclerosis in the animals. At the same time there is an increase in the chemiluminescence intensity of apo-B-containing lipoproteins in the presence of divalent iron, reflecting the enhancement of lipid peroxidation in apo-B-containing lipoproteins of rabbit blood serum. The increased chemiluminescence of apo-B-containing lipoproteins within the early stages of experimental atherosclerosis can be used for early diagnosis of atherosclerosis on an experimental and clinical basis.
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The authors followed the time course of the psychic disturbances in 37 patients with primary biliary liver cirrhosis who received hemosorption as part of the combined therapy. The peculiarities of the psychic disturbances and their time course before and after the hemosorption were specified. It was found that after the hemosorption a regression of asthenoneurotic disturbances took place. However, the characteristic changes and elements of the psychoorganic syndrome developed in the course of the disease showed no positive dynamics.
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