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Biomedical subjects

M Neumann

Publications and source records attributed to M Neumann.

At least 145 records · Page 8Linked to original sources
PubMed1983

[Chemotherapy of small cell carcinomas of the lung].

This report gives a comparison of two polychemotherapeutic regimen: Vincristin-Adriamycin-Cyclophosphamide (VAC) versus Vinblastin, Methotrexate, Fluoro Uracil, Cyclophosphamide (Israel-Karrer-Sighart regimen). 35 patients have been treated with VAC, 27 with IKS, some of them received additional irradiation. Response was quite similar in both regimens, survival was significantly increased for patients treated with VAC (49 weeks medial survival time versus 31 weeks). Best results were obtained in combination with intermittent radiotherapy (so called "sandwich-method"), survival time in this treatment had been 73 weeks. Side effects of the chemotherapy were tolerable and not severe. VAC in extensive disease alone and in limited disease in addition to radiotherapy can, therefore, be recommended in outdoor-patients treatment in small cell carcinoma of the lung.

Carcinoma, Small Cell↗
PubMed1983

Uterine motility after post-partum application of sulprostone and other oxytocics.

UNLABELLED: With the introduction of prostaglandins to obstetrics another group of substances was known to influence uterine motility also post partum. It was interesting to study the effect of equal doses of synthetic prostaglandin E2 (sulprostone), methergin and synthetic oxytocin on the so-called puerperal model in humans. By transcervically introduced twin-catheters uterine motility was recorded after uncomplicated pregnancy and delivery in 101 volunteers. Uterine motility was recorded and evaluated according to the onset of the effect, its duration, motility pattern and uterine activity. Maternal heart-rate was additionally recorded similarly to the feto-maternal cardiotocogram. All substances were applied by intramuscular injection. The following observations could be made: 1. Onset: sulprostone is effective in the shortest time, followed by oxytocin and methergin. 2. DURATION: the most prolonged effect is noticed with methergin, followed by sulprostone and syntocinon. 3. Motility pattern: the strongest effect can be seen with sulprostone, followed by methergin and syntocinon. 4. Increase of uterine motility was highest with sulprostone, followed by methergin and oxytocin. 5. No side-effects on the maternal heart-rate could be found with any of the tested substances. As a conclusion, sulprostone is recommended in the treatment of severe bleeding post partum when an immediate and long-lasting effect is to be achieved with one single substance.

Dinoprostone↗
PubMed1982

Hypersensitivity to tobacco antigens in smokers and nonsmokers.

The examinations were carried out in 336 tobacco smokers, 91 persons who gave up smoking, 175 persons exposed to tobacco smoke indirectly and 112 persons who had nothing to do with tobacco smoke. Together 714 persons were examined. The examinations, which were carried out on the grounds of the clinic observations and the data obtained from interviews, aimed at the discovering of the causal nexus between the attacks of atopic bronchial asthma as well as the occurrence of acute urticaria and the exposure to tobacco smoke. All the patients underwent the dermic allergometric test with the extract from cigarette tobacco. The results of these examinations have not delivered any evidence concerning the allergenic reaction of the immediate type to tobacco smoke.

Allergens↗
PubMed1980

[HBs-antigenemia in patients with pulmonary tuberculosis (author's transl)].

1637 patients of a department for lung tuberculosis were tested for HBs-antigen. 32 patients (1.95%) were found to be HBs-antigen-positive. This incidence is higher than in patients of an internal clinic and much higher than in the middle-european population at the same time. In no positive case acute hepatitis could be diagnosed. The hospitalization time was prolonged in the positive cases.

Adolescent↗
PubMed1980

[Hematogeneous metastases in small cell carcinoma of the lung (author's transl)].

The autopsy findings in 202 cases of small cell carcinoma of the lung are analyzed. The distribution of hematogenous metastases is compared with the findings of other investigators. Summarizing the autopsy findings in 975 cases the incidence of metastases in liver, bone marrow, adrenals and brain is shown. The prophylactic brain irradiation as routine regimen in small cell carcinomas of the lung cannot really improve the results of treatment since only 25% of all cases have metastases in the brain.

Adrenal Gland Neoplasms↗
PubMed1980

[Folliculitis caused by pityrosporum].

A 21 year old woman with folliculitis caused by Pityrosporum is described. Differential-diagnosis especially with regard to acne vulgaris is discussed.

Adult↗