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Biomedical subjects

M Nyström

Publications and source records attributed to M Nyström.

At least 73 records · Page 4Linked to original sources

Signs and symptoms of craniomandibular disorders in a series of Finnish children.

The prevalences of subjective symptoms and clinical signs of craniomandibular (CM) disorders, orofacial parafunctions, and occlusal conditions were determined in a series of Finnish children (n = 166). All were first interviewed, and then 156 of them were examined clinically. Fifty-two per cent of the children reported at least one subjective symptom, and 75% at least one parafunctional habit. Clinical signs were common but rarely severe in accordance with Helkimo's clinical dysfunction index (Di). Both the number of subjective symptoms (p less than 0.001) and the number of orofacial parafunctions (p less than 0.05) correlated with the clinical dysfunction index.

Adolescent↗

Dental maturity in Finnish children, estimated from the development of seven permanent mandibular teeth.

Overall dental maturity was studied semilongitudinally in a group of 248 healthy children born in Helsinki in 1968-73. In all, 738 orthopantomograms were taken of these children at ages of 2.5-16.5 years. Overall dental maturity was estimated by the method of Demirjian and Goldstein, which is based on the development of seven left mandibular permanent teeth. The aim of the study was to construct dental maturity curves for Finnish children and to compare their dental maturity with that of French-Canadian children studied by the same method. The Finnish children were more advanced in dental maturation than French-Canadian children (p less than 0.01). In boys the advancement was seen at the age of 5-10 years and in girls at the age of 4-12 years. These findings suggest differences in overall dental maturity among white population groups.

Adolescent↗

MMC-E cells--origin and changes in karyotype accompanying malignant transformation.

Karyotype analysis of an established nontumorigenic cell line (MMC-E) indicated that the cells are of rat origin instead of mouse, as interpreted earlier. This cell line, now termed RE (rat epithelial) had a karyotype of 39,X,-5,-15,-?16,+t(3q11q) in the stem line. There was also one subline that had a karyotype of 40,X,-5,-15,-?16,+t(3q11q), +?t(5;?). Chromosome changes and frequency of sister chromatid exchanges (SCEs) were studied from seven malignantly transformed RE cell lines. These included cells transformed by Moloney murine sarcoma virus, the acute transforming retrovirus 3611-MSV, murine leukemia virus, or ethylnitrosourea. Changes in chromosomes #3 and #5 seemed to be associated with malignant transformation of RE cells. In addition to the t(3q11q) and monosomy for chromosome #5 seen in the parent cell line, monosomy for chromosome #3 and the t(5;?) were observed in all malignant cell lines. The latter changes either were absent (monosomy for chromosome #3) or present only occasionally [t(5;?)] in the parental cells. The results of SCEs showed that the malignantly transformed cell lines do not have increased frequency of SCEs as compared with that of the parental cell line.

Animals↗

Rubella immune state and rubella vaccination of female university students.

At the Finnish Student Health Service, we have measured rubella antibodies in 3 consecutive academic years--1979-80, 1980-81 and 1981-82--in 2 483 first year female students. In 1979-80, 16.4% were seronegative, the following year the figures were 10.4% and in the third year 7.4%. Among students less than or equal to 19 yr of age the seronegatives decreased from 19 to 2% in 3 yr. This decrease shows that the national rubella vaccination programme which began in 1975 has been more successful than expected. A hemolysis-in-gel (HIG) test has proved a suitable screening method and the health examination of first year students a suitable occasion to test the immunity against rubella. Seroconversion occurred in 81.4% of those vaccinated.

Adult↗