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Biomedical subjects

M Occhiogrosso

Publications and source records attributed to M Occhiogrosso.

At least 19 recordsLinked to original sources
PubMed1996

Choroid plexus compression of glossopharyngeal nerve in patients with glossopharyngeal neuralgia.

Compression of the glossopharyngeal nerve by the lateral choroid plexus of the 4th ventricle protruding excessively through the foramen of Luschka may be at the basis of some forms of glossopharyngeal neuralgia. This condition was observed in four patients. In one case, an anterior compression of the 9th nerve by a megadolic vertebral artery was also present. The condition was resolved in all patients by separating the nerve from the plexus and transecting it at the level of the foramen of Luschka.

Aged↗
PubMed1991

Prenatal diagnosis of craniopagus.

The long-term prognosis of craniopagus, a congenital abnormality of monozygotic twinning, is strictly correlated to the type of shared cerebral structures. Hence, the purpose of prenatal diagnosis is not only to detect this malformation, but also to identify the fused cerebral structures. The authors report a prenatal diagnosis of a craniopagus during the second trimester of pregnancy. Comparison of ultrasound data with the pathological findings underlines that ultrasound is of great value in detecting malformations, but it is not alone sufficient to identify the types of conjoined cerebral structures.

Adult↗
PubMed1990

Prediction of the interaction effects Ar+ laser-brain tumours by study of the photoacoustic spectroscopy of cerebral oncotypes.

A preliminary definition of light absorption spectra of brain neoplasm represents a correct approach to the laser therapy of cerebral tumours. The goal should be the identification of those oncotypes more sensive to the laser energy, allowing consequently a dosage of the energy proportional to the light absorption coefficient, reducing any side effects. With this purpose the coefficients of light-absorption of 63 different brain tumours have been analyzed and defined by means of photocoustic spectrometry. The study has been focused at wavelength of the Ar+ laser (4,600-6,000 A). The results show a close relationship between histology, degree of vascularization and/or pigmentation and light absorption: the more immature and/or pigmented oncotypes show the highest coefficients of optical absorption. In the laser therapy of these neoplasms it will be sufficient to use low powers and short exposure time.

Animals↗
PubMed1986

Evaluation of the Ar+ laser thermal effect in rabbit brain tissue by means of optical absorption coefficients. Photoacoustic measurements.

In predicting Ar+ laser-neural tissue interaction a determination of the optical absorption properties of brain parenchyma appears indispensable. In this study a determination of absorption spectra of different areas of rabbit brain at the wavelength of an Ar+ laser beam is made. The areas considered in the study are frontal and occipital gray and white substance, thalamus, basal ganglia, cerebellar cortex and choroid plexus. Specimens of these areas measuring 2 X 3 X 3 mm were obtained from coronal sections 1 cm thick of 20 rabbit brains. The analysis of optical properties was made by means of a photoacoustic spectrometer which appears the only suitable technique for testing the optical absorption properties of biological materials. The absorption coefficient results were similar in magnitude and constant in all the areas examined, measuring approximately 50 cm-1. The prediction of lack of any selective effect for the different areas is confirmed by the sizes of lesions made in cerebral specimens of the same areas of the contralateral hemisphere by means of Ar+ laser: the lesions increase in size in proportion to the increase in output power and exposure time, independently of the areas considered. Also the histological examination of the areas shows the same morphology to be independent of the variations of both output power and exposure time. The only differences were the presence for short exposure time and low output power of a carbonized layer inner to the layer of coagulative necrosis.

Absorption↗
PubMed1983

Brain-stem hemangioma calcificans. Case report.

A case of brain-stem hemangioma calcificans is described. The few cases reported in the literature prove the rarity of this tumor, which is considered a benign variant of cerebral cavernous hemangioma. Diagnosis and treatment of these tumors are briefly discussed with a review of the literature including 11 previous cases.

Adult↗
PubMed1980

Glossopharyngeal neuralgia due to exuberant choroid plexus.

The case of a 73-year-old woman with a glossopharyngeal neuralgia due to compression of the 9th nerve by the lateral choroid plexus of the 4th ventricle excessively protruding through the foramen of Luschka is reported. No similar cases are described in the literature. Such an eventuality should be suspected and verified in the presence of a glossopharyngeal neuralgia in which no other causal factors can be demonstrated.

Aged↗
PubMed1979

Intramedullary thoracic schwannoma.

A case of intramedullary thoracic schwannoma in a 40-year-old woman without signs of von Recklinghausen's disease is reported and the hypotheses as to its origin are discussed. The literature covering 11 other cases is reviewed.

Adult↗
PubMedDate not supplied

Ultrastructural and morphometric investigation of human brain capillaries in normal and peritumoral tissues.

Capillaries of peritumoral and normal brain tissues were ultrastructurally and morphometrically investigated to evaluate the changes in peritumoral capillaries connected with the tumor-associated vasogenic edema. The endothelial cells of peritumoral capillaries showed varying thickness, electron-lucent cytoplasm, and structurally normal tight junctions. The basal lamina was thickened, rarefied, and vacuolated. The pericytes were provided with pinocytotic vesicles and phagocytic bodies. The astrocytic glia appeared empty or swollen, with few glycogen granules and a disarranged cytoskeleton; well-preserved glia was occasionally observed. The brain tissue was slightly edematous. No statistically significant differences were observed between normal and peritumoral capillaries as regards diameter, wall thickness, endothelial thickness, and endothelial vesicle density. Instead, the peritumoral capillaries displayed three times as many endothelial surface-connected vesicles, a markedly thicker basal lamina, and significantly reduced extension of pericytic and glial investments. The kind and severity of the vascular modifications, compared with the slight edematous appearance of the nervous tissue, strengthen the hypothesis that peritumoral capillaries could be involved in the edema resolution process.

Astrocytoma↗
PubMedDate not supplied

Inhibiting action human glioblastoma extract on haemolytic complement of human and xenogeneic sera.

The action of some extracts of human glioblastoma of the haemolytic complement of human and xenogeneic sera has been examined. The study suggests that the antigenic products of some human glioblastomas may induce an inhibiting effect on the haemolytic complement of human, as well as xenogeneic (rat and rabbit), sera. The inhibiting action on the xenogeneic sera is indicative of the presence of species-specific antigens or tumor cells, comparable to that of normal tissues.

Animals↗
PubMedDate not supplied

Malignant cerebellar astrocytoma. Report of five cases.

Five cases of malignant cerebellar astrocytoma observed during a seven-year period are reported. The analysis of the cases allows us to conclude that malignant cerebellar astrocytoma represents a true tumoral entity quite distinct from cerebellar glioblastoma as well as from medulloblastoma. A perfect correspondence between the histological malignancy and the duration of survival has been noted in all the cases.

Adult↗
PubMedDate not supplied

Forth ventricle hematoma in a eight-year-old child.

We report the case of a 4th ventricle hematoma due to rupture of an angioma localized in the cerebellar vermis, in an eight-year-old child. Only seven cases of a vascular malformation in such a localization, angiographically and/or pathologically verified, have been previously reported. The girl died, in spite of prompt surgical treatment. Also the clinical presentation of this kind of case is very rare.

Cerebellar Neoplasms↗