PubMed Health⌕ Search

Biomedical subjects

M Occhiogrosso

Publications and source records attributed to M Occhiogrosso.

22 records · Page 2Linked to original sources
PubMedDate not supplied

Antigenic properties of fresh and lyophylised human dura mater.

The action of human fresh and lyophylised human dura mater on rat, rabbit and human serum complement has been analyzed with the aim of confirming and comparing the species-specific antigenicity of both substances. The results demonstrate that both fresh and lyophylised human dura mater induce a complement consumption on rat and rabbit serum. The phenomenon is related to the species-specific antigenic activity of the tissue, and it is only partially decreased by the lyophylisation procedure. The residual antigenic activity, however, doesn't limit the use of this material as a graft for dural defects repairs in humans.

Animals↗
PubMedDate not supplied

Polyamines: current review and their perspectives in neurosurgery.

A short review of polyamines and their possible clinical interest and applications in the field of brain neoplasms is presented. Dosage of CSF polyamines was proved to be useful in monitoring patients with medulloblastomas and others malignancies with meningeal involvement. Polyamines and their enzymes in neoplastic tissue may correlate to tumor growth. Inhibition of polyamines synthesis by drugs may be a possible way of slowing down tumor growth.

Animals↗
PubMedDate not supplied

In vitro inhibition of rat serum complement activity by an extract of lyophilised human dura mater.

The inhibiting effects of an extract of lyophilised human dura mater on the complement activity of rat serum have been studied in order to evaluate a possible species-specific antigenic activity in this material generally used in the repair of dural defects. The results demonstrated that the extract may inhibit complement activity of rat serum. The phenomenon resulted to be of low entity (nearly 20% of mean value) and was due to the interaction between tissue species-specific antigens and natural antibodies of rat serum. The residual antigenic activity may limit the use of this material only in xenogeneic graft recipients.

Animals↗