Biomedical subjects
Publications and source records attributed to M Parma.
In the context of a study project on acute cerebrovascular diseases carried out for just a year by both hospital and university units of Parma (Italy), computer-aided charts for coding CT-scan and arteriographic findings were designed. Their models are reported.
A patient with a right temporal lesion is described who, in recognising sounds and noises, complained of deficits which seemed to be most evident when sounds and noises could be recognised mainly by timbre whereas no deficit was noticed when pitch and rhythm were the main indicators. In addition, some global distortions in musical appreciation were complained of and described as "resonance" or "loss of aesthetic pleasure".
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Sixty right-handed non-musician subjects, thirty males and thirty females, and thirty right-handed musician subjects, seventeen males and thirteen females, were submitted to dichotically presented tonal sequences. Immediate identification procedure with preliminary training was used. The results point out that both, musicians and non-musicians, males and females, show significant left ear dominance. The left ear dominance was more frequent in musicians. The results are discussed in the light of the "analytic-synthetic" theory of Bever and Chiarello and the "temporal" theory of Gordon.
A case of transient global amnesia has been neuropsychologically assessed during the attack. Global involvement of any memory modalities and far-reaching retrograde amnesia were found. Follow-up retesting, 1 week and 6 months later, showed persistence of mild verbal memory impairment.
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Two cases of transitory ischaemic attacks, which occurred during progestogen therapy, are reported. Clinical history and symptoms of both patients suggested migraine disorder. Therefore, the hypothesis is made that also progestogen-only preparations, likewise oestrogen-progestogen oral contraceptives, may cause neurological troubles by vasomotor mechanisms.
Therapeutic effectiveness of lithium carbonate in cluster headache is confirmed on the ground of the results in 20 patients (14 with the episodic form, 6 with the chronic one). Outstanding findings were: a) the early effectiveness; b) the occurrence of therapeutic effects even with low doses; c) the negligible risk of side effects. The way interrupting the treatment in episodic cluster headache is proposed. In chronic cluster headache recurrence can be expected when lithium is stopped, but in some cases it occurs after a long free interval. The contrast is stressed between the high efficacy in all the 20 patients with cluster headache and the complete uneffectiveness in 5 patients affected by headaches considered as borderline between cluster headache and migraine.
Sixteen patients, who had suffered only one episode of transient global amnesia and showed no clinically evident abnormalities in their follow-up, were examined with psychometric and memory tests. Deficits in verbal long-term memory and in verbal IQ were found. These observations seem to demonstrate that in transient global amnesia patients regarded as being 'normal' in their follow-up there is no complete recovery and the sequelae seem to conform to a definite pattern. Problems of nosology and localization are discussed.
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Twenty-one patients showing memory deficits were submitted to neuropsychological battery, before and after treatment with Deanol. No significant effect has been found. Arguments suggesting further investigation are discussed.
We investigated the number of echinocytes, the serum hemopexin level, and spectrin band II phosphorylation in the blood of normal subjects, patients, and carriers of Duchenne dystrophy. The patients and carriers exhibited quantitatively significant differences with respect to controls.
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Dichotic listening was studied in two groups of temporal epileptics with monolateral circumscribed EEG focus: the first presenting with signs of brain damage and the second free from these signs. The lesional group tended to prefer the ear ipsilateral to the side of lesion, while subjects with non-lesional focus tended to prefer the ear contralateral to the side of focus. The results are discussed and compared with other observations in this field.
Because of previous reports of a possible correlation between echinocytogenesis and muscular dystrophies, we investigated the time-dependent development of echinocytes in the blood of normal subjects, patients, and healthy carries of Duchenne dystrophy. There was a quantitatively significant increase of echinocytes in patients and carriers.