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M Pellegrin

Publications and source records attributed to M Pellegrin.

5 recordsLinked to original sources
PubMed1980

Granulomatous hepatitis in Q fever.

Liver lesions in 17 patients with serologically diagnosed Q fever are described. A distinctive granulomatous pattern, with granuloma formation plus a fibrinoid ring, was observed in 14 cases. In two cases the fibrinoid material consisted of fibrillar eosinophilic structures without an annular arrangement, interspersed among epithelioid cells. In only one case was a nonspecific granuloma (devoid of fibrinoid material) noted. We conclude that the association of a granuloma with fibrinoid material is highly indicative of Q fever, but serial sections are often necessary to demonstrate this pattern.

Adult↗
PubMedDate not supplied

[Collagenous colitis].

The authors report two new observations of collagenous colitis. In both cases the signs were of functional colonopathy, and the diagnosis was only made after rectal and colic biopsies. In one case, electron microscopy revealed that the collagen band was independent of the epithelial membrane. The collagenous deposit contained many nerve endings, which seems to suggest an inflammatory origin of the disease. The clinical condition of a female patient was greatly improved by mepacrine, but the histological lesions remained unchanged.

Colitis↗