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Biomedical subjects

M Pilarczyk

Publications and source records attributed to M Pilarczyk.

At least 19 recordsLinked to original sources
PubMed2003

Hemiballismus following general anesthesia. A case report.

Hemiballismus is characterized by the abrupt onset of violent proximal flinging movements, affecting the limbs, neck and trunk on one side of the body. It is caused by the lesion in the region of the contralateral subthalamic nucleus of the Luys. Usually it is a self-limiting disease, lasting 6-8 weeks. A 49-year-old man has been admitted to the hospital after flinging movements of his right arm and the right side of the trunk occurred. A few days earlier he had undergone general anesthesia prior to a dental procedure. There was trouble in waking the patient afterwards. The movements lasted a few days. MRI of the brain revealed ischemic lesions areas in T2-weighted images localized in the region of globus pallidus bilaterally. EEG was abnormal, and showed slowed background activity with slow waves in left temporal lobe. He was treated with haloperidol, clonazepam and vasoactive medications. In spite of administered treatment, hemiballic movements reappeared occasionally. Due to increased frequency of the movements the patient was hospitalized again two years later. The second MRI revealed changes described earlier and a new ischaemic focus in left parietal lobe. Continuation of treatment with haloperidol was administered.

Anesthesia, General↗
PubMed2002

Using different types of capillary chromatographic columns as denudation traps: a comparison of sorption properties.

The research presented concerns segments of capillary chromatographic columns of different types (WCOT, SCOT, PLOT) used as traps for collection of samples of volatile organic analytes from a stream of air utilizing the equilibrium denudation technique. During the model experiments (utilizing standard mixtures), values of the partition coefficients (Kfs) were determined for volatile organic compounds frequently occurring as pollutants of atmospheric air (benzene, toluene, ethylbenzene, o-xylene, chlorobenzene). The conducted research demonstrated that the stationary phase film thickness did not affect the partition coefficient value. It was also proved that there is no dependence between the manner of applying the stationary phase in the column and the partition coefficient value.

Adsorption↗
PubMed2002

The application of an open tubular trap in analysis of organic air pollutants.

The paper presents the studies on equilibrium trapping of organic air pollutants. A piece of a commercial capillary chromatographic column coated with polydimethylsiloxane was used for trapping. This kind of the trap was applied for sampling and enrichment of selected volatile nonpolar organic compounds from workplace atmosphere (woodworking shop). In the method developed, which is based on equilibrium trapping the concentration of analytes in a studied medium can be calculated from the partition coefficients determined in a calibration step and the amount of particular analytes trapped. Simultaneously with equilibrium trapping, analytes were sampled into sorbent packed tubes. The concentrations of analytes in woodworking shop atmosphere obtained with both sampling methods (equilibrium and dynamic) were in good agreement.

Air Pollution, Indoor↗
PubMed1999

[General cerebral and systemic metabolic disturbances occurring in ischemic stroke with special emphasis on glucose and its metabolites].

Ischaemic stroke is a stressogenic factor triggering a complex defensive reaction called "alarm reaction" by Selye. Stress gives rise to liberation of catecholamines, dopamine beta-hydroxylase in the blood, cerebro-spinal fluid and urine. Patients with ischaemic stroke were found to have increased adrenaline, noradrenaline, and 3-metoxy-4-hydroxymandelic acid level in urine and increased cortisol level in blood serum. Patients, especially those with severe ischaemic stroke have increased concentrations of glucose metabolites in blood and cerebro-spinal fluid: pyruvate acid, lactic acid, acetylacetic acid and hydroxybutyric acid.

Epinephrine↗
PubMed1999

[Evaluation of lactic acid levels in blood of patients with ischemic stroke in the earliest stage of the disease].

The aim of the study was the assessment of concentrations of lactic acid in the blood of patients with mild course and severe course of ischaemic stroke in the earliest stage of the disease. The subject of the study were 20 patients with a mild ischaemic stroke and 20 patients with a severe one on its 1st, 3rd and 7th day. Enzymatic method for determining lactic acid content in the blood was used (the kits Test-Combination Lactate fully enzymatic of Boehringer Mannheim). In the group of patients with mild ischaemic stroke increase values of lactic acid were shown on all days of the disease, but the differences were statistically insignificant. In patients with severe ischaemic stroke these values were higher than in controls, and the differences were statistically significant. The study showed a positive correlation between high concentrations of lactic acid and severe clinical condition of patients.

Cerebral Infarction↗
PubMed1999

[Evaluation of pyruvic acid concentration in blood of patients with ischemic stroke in the earliest stage of the disease].

The aim of the study was the assessment of concentrations of pyruvic acid in the blood of patients with mild course and severe course of ischaemic stroke in the earliest stage of the disease. The subject of the study were 20 patients with a mild ischaemic stroke and 20 patients with a severe one on its 1st, 3rd and 7th day. Enzymatic method for determining pyruvic acid content in the blood was used (ready made reagents Test-Combination Pyruvate by Boerhinger Mannheim). In the group of patients with mild ischaemic stroke the concentrations of pyruvic acid were increased on all days of the disease, compared with controls, but the differences were statistically insignificant. In the group of patients with severe ischaemic stroke the concentrations of pyruvic acid were higher than the ones in control group, but only on the 1st and 3rd day of the disease the differences were statistically significant. The results of determinations indicate that there is a positive correlation between levels of pyruvic acid and severity of the clinical course of the disease.

Cerebral Infarction↗
PubMed1995

Brain neoplasms with development similar to transient brain ischaemia.

Diagnostics of brain tumours still remains a serious problem in neurologist's career. Difficulties in proper diagnosing refer mainly to endocranial tumours with atypical clinical course. Frequency of brain tumours' vascular manifestation is assessed as 1-4%, and in most cases it is the kind of manifestation which corresponds with intracerebral bleedings and more seldom with ischaemic strokes. Reports on brain tumours with developments similar to transient brain ischaemia (1, 2, 3, 4) are published occasionally. In Neurology Clinic of the Medical Academy in Lublin, we conducted observation of two patients with brain tumours (one metastatic and the other one-primary), where the former as well as the latter case were treated as cerebral circulation failures at their initial stage. Application of typical vasoactive treatment brought about temporary regression of symptoms.

Aged↗
PubMed1995

The influence of Nootropil on the content of inorganic phosphorus and lipid phosphorus in the blood of patients with intracerebral haemorrhage.

Nootropil exerts positive impact on both intracortical and cortico-subcortical conduction and increases ATP content in the nerve cell which leads to the increase of ribonucleic acid's synthesis necessary for long duration memory and proteins essential for the production of enzymes (3). The cerebral stroke can change the activity of the central vegetative neurons and induce generalized disturbances of the mechanism of metabolism, e. g. in phosphorus and phospholipid economy (1, 2).

Cerebral Hemorrhage↗
PubMed1995

Does a spasm of vertebral canal exist?

During myelographic examination the travel of a contrast medium through the vertebral canal can be observed when it is applied by the lumbar puncture. When the vertebral canal is totally obstructed the contrast medium stops at the verge of the closing forming sometimes (in case of tumours) concave meniscus. In case of incomplete block of the canal the contrast medium flows around the obstacle. Results of myelographic examination do not leave much room for doubts as to the character of discovered disease process. They are very often confirmed during follow up computer tomography imaging of the suitable segment of the spinal column. In some patients being under clinical observation in this Department of Neurology, however, it was difficult to arrive at a specific diagnosis on the basis of the examination of their vertebral canal by means of the contrast medium in spite of the abnormalities observed repeatably and the concomitant severe progressive lessions of their spinal cords.

Contrast Media↗