PubMed Health⌕ Search

Biomedical subjects

M Radke

Publications and source records attributed to M Radke.

46 records · Page 3Linked to original sources

[Qualitative and quantitative behavior of B-lymphocytes and immunoglobulins in the serum of children with acute leukemia after a single immunoglobulin concentrate substitution].

In 19 children affected with acute leukaemia the serum immunoglobulin level was examined. An Ig deficiency treated with a single administration of IgA or IgM concentrate could be detected in 16 of these children. The impact of this single Ig substitution on the serum immunoglobulin level and on B-lymphocytes in the peripheral blood was thrice examined after this substitution. A significant increase of the corresponding Ig class in the serum and a significant decrease of B-lymphocytes in the peripheral blood could be observed.

Adolescent↗

[Quantitative behavior of B-lymphocytes in infection susceptible children following a single therapeutic substitution with human gamma globulin].

In 15 children with a lowered gammaglobulin level a single substitution with HGG was made, with the impact of this substitution on the number of B-cells in the peripheral blood being examined by means of the direct fluorescence antibody technique. In 9 from 15 children the substitution had no influence on the number of B-cells. However, a significant increase of the number of B-cells could be observed in 6 from 15 children. 14 days after the substitution the number of B-cells lay within the normal range again.

Agammaglobulinemia↗

[Delayed fontanelle closure in infants with cyanotic cardiomyopathies].

In comparison with infants not suffering from cyanotic heart failures a different size (width and length) as well as a delayed time of closure of the anterior fontanelle in infants with congenital cyanotic heart failures were detected. In these patients typical phenomenons by ultrasound examinations are described also.

Cephalometry↗

[Rhabdomyolysis as a rare complication of severe hypertonic dehydration--a case report].

Rhabdomyolysis can be caused by aetiologic completely different factors. It can occur only few hours following beginning of enteritis and refusal of ingestion. We report the case of a 5 month old male infant, which showed the clinical characteristics of a hypertonic dehydration on admission to hospital. Serum levels of transaminases, creatinine, urea, lactated hydrogenase, creatine kinase and urinary excretion of myoglobin were highly elevated. Forced diuresis, compensation of acidosis and electrolyte disturbances could prevent the development of an acute renal failure--the most important complication of rhabdomyolysis. The boy could be discharged without any residuals of this episode of disease.

Acute Kidney Injury↗

Candidosis of the urinary tract with padding phenomenon of the renal pelvises in an infant with obstructive uropathy.

A male infant with obstructive uropathy developed yeast cell agglomerations which were detectable macroscopically and by image-generating techniques within both renal pelvises after Candida albicans infection of the urinary tract. Therapy with flucytosine induced excretion of 'fungal balls' via the urethra. Continuation of therapy with liposomal amphotericin B (AmBisome) prevented a relapse after development of fungal resistance against flucytosine. Sonographically or radiographically detectable formation of 'concrements' within the urinary tract of patients with an immature or compromised immune system and additional features such as obstructive urinary tract should suggest a localized or systemic mycosis, particularly in the context of long-term antibiotic treatment.

Amphotericin B↗