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Biomedical subjects

M Rees

Publications and source records attributed to M Rees.

At least 127 records · Page 7Linked to original sources
PubMed1989

Long-term recurrence patterns following proximal gastric vagotomy.

Two hundred and forty-two consecutive patients were prospectively followed up following elective proximal gastric vagotomy (PGV) for duodenal, pyloric or prepyloric ulceration. There was no operative mortality and no case of lesser curve necrosis. Five to 15 years follow-up have been completed. One hundred and eighty-three patients were assessable (80% of survivors) and 29 of 33 symptomatic patients attended for endoscopy. Fourteen recurrent ulcers had been diagnosed previously and six new recurrences were diagnosed, giving a total recurrence rate of 11%. Seven of these were transient/innocuous and 13 (7%) were chronic/malevolent recurrences. The majority (70%) of recurrences occurred in the first 5 years of follow-up and only one recurrence occurred later than 10 years' follow-up. More than half (56%) of the operations were performed utilizing Burge intra-operative testing and 44% without Burge testing. No difference in recurrence rates was apparent between these two groups. In seven patients with pyloric or prepyloric ulceration, three (43%) developed a chronic recurrence. PGV is a safe, surgical treatment for duodenal ulceration, offering acceptable recurrence rates and a very low mortality and low incidence of side-effects. The majority of recurrences occur early in the follow-up period. Burge intra-operative testing provides no clear reduction in recurrence rates. PGV should not be used for pyloric or prepyloric ulceration.

Adolescent↗
PubMed1989

Congenital pilonidal sinus of the nose.

The aetiology of pilonidal disease, which occurs frequently in the sacrococcygeal region, is uncertain; whether it is congenital or acquired has been debated considerably. An instance of pilonidal disease, occurring at a previously unreported site, and of definite congenital origin, is reported.

Adolescent↗
PubMed1989

HIV infectiousness and the AIDS epidemic.

The paper outlines a theory of the AIDS epidemic based on assumptions regarding the changes in infectiousness over the life cycle of the disease. It proposes a short initial period of infectiousness, followed by a long dormant period, which is in turn succeeded by another period of infectiousness, longer than the first period. Each of the two periods of infectiousness can generate an associated epidemic. It is suggested that the Western homosexual epidemic is based on initial stage infectiousness, while the African heterosexual epidemic is mainly the result of end stage infectiousness.

Acquired Immunodeficiency Syndrome↗
PubMed1989

Forearm blood flow measurements using technetium-99m human serum albumin following brachial arteriotomy.

A simple, low cost method for measuring forearm blood flow during reactive hyperemia has been developed. Subjects are seated with hands and forearms over a large field-of-view gamma camera. Blood pressure cuffs inflated above the elbows isolate the blood in the forearms and hands and induce a hyperemic response. The remaining blood pool is labeled with technetium. The rate of increase of activity following release of the cuffs is measured from the gradient of time-activity curves and is calibrated for flow by counting a venous blood sample. The technique has been applied to a group of normal controls and to symptomatic and asymptomatic patients following right brachial arteriotomy. Forearm blood flow in normal subjects was 32.9 +/- 6.4 ml/100 ml/min and for subjects with occlusion of the brachial artery was 6.4 +/- 2.1 ml/100 ml/min. The method is simple, widely available, and reproducible. The good signal to noise ratio allows it to be used in cases of very low flow either as an aid to diagnosis or to measure treatment response.

Adult↗
PubMed1988

Sectional and segmental variability of left ventricular function: experimental and clinical studies using ultrafast computed tomography.

In this study, ultrafast computed tomography, a new high spatial and temporal resolution imaging system, was employed to define the range of sectional (tomographic) and segmental left ventricular function in 11 normal anesthetized dogs and 11 normal human volunteers. After intravenous infusion of contrast agent, multilevel tomographic images of the left ventricle (apex to base) were acquired at a rate of 17 frames/s. Analysis of these studies demonstrated substantial but predictable heterogeneity in left ventricular contraction from apex to base. In dogs and humans, for example, the average tomographic ejection fraction of the most basal level of the left ventricle was 40% less than that of the most apical level (p less than 0.05). In humans, circumferential segmental cavity contraction at the mid-papillary muscle level was relatively homogeneous (range 50 to 92% for 12 wedge-shaped segments around the tomographic circumference) if the reference system employed an endocardial centroid, but was less uniform if it used an epicardial centroid (range 22 to 98%). It is concluded that contraction of the normal left ventricle in dogs and humans is heterogeneous both between levels (apex to base) and within a single level (circumferential cavity contraction). However, the patterns of cavity contraction from apex to base and circumferential segmental cavity contraction within a given level as defined by ultrafast computed tomography are sufficiently narrow and predictable in normal individuals that these variables may be useful to define regional contraction abnormalities in pathologic conditions.

Adult↗
PubMed1988

Dysmenorrhoea.

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Dysmenorrhea↗