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Biomedical subjects

M Resl

Publications and source records attributed to M Resl.

At least 37 records · Page 2Linked to original sources
PubMed1995

[Carcinoid tumorlets and pulmonary hypoxia].

Relationship between carcinoid tumourlets and chronic pulmonary hypoxia was studied on a group of 29 patients coming to necropsy (25 cases) in the last 25 years or surgically treated (4 cases) for non-neoplastic pulmonary lesions. All tumourlets expressed the argyrophilia and were immunoreactive for neurone-specific enolase. Pulmonary hypoxia was studied according to the presence of chronic bronchitis, emphysema and microscopical signs of hypoxic arteriopathy. Cigarette smoking was an additional criterion. The results indicated a strong relationship between tumourlets and chronic pulmonary hypoxia. 79% of patients with tumourlets have had the emphysema and in 41% of examined cases with this lesion the chronic bronchitis was diagnosed. The hypoxic arteriopathy was present in 48% of subjects with emphysema and 27% of cases with bronchitis. It was found in the same number of patients with both the examined lung diseases. On the other hand, the possibility of other cause of neuroendocrine cell hyperplasia was to be considered in 17% of investigated subjects in whom no evidence for the above mentioned relationship was found.

Adult↗
PubMed1993

[Mycoses of the heart].

There is an increasing frequency of heart mycoses. Authors identified 19 such cases between 1972 and 1991, 63% in the last 6 years (frequency was 0.1% in 17.661 autopsies of patients over 7 days of life). Males prevailed (17:2). Yeasts of genus Candida dominated, unusual etiology represented Candida parapsilosis, Torulopsis candida and Aspergillus restrictus. Sampling from vegetations or abscesses was a prerequisite for positive autoptic cultivation. Probable source of infection was found in 12 patients and 5 of them had an infected thrombosis of venous catheter. Mycosepsis comprised nearly equal number of endocarditides (mostly left sided) and myocarditides. Spread of endocardial infection into myocardium was rare, most myocarditides resulted from disseminated infection in immunocompromised patients. Endocarditides mainly complicated surgical interventions.

Adolescent↗
PubMed1991

[The dynamics of the morphological changes in the tissues after the subcutaneous administration of vaccines against Q fever].

The comparative study of the dynamics of morphological changes in tissues of guinea pigs after the subcutaneous injection of chemical, live and combined vaccines against Q fever during the period from 12 hours to 90 days was made. All vaccines under study were shown to produce a pronounced local damaging effect. Two periods were tentatively discriminated in the dynamics of changes: the early phase (till 48 hours) and the late phase (days 2-90). At the early stage the most pronounced changes were registered after the injection of the combined vaccine. At the late phase the use of the chemical and combined vaccines was accompanied by the appearance of secondary hemorrhages into newly formed connective tissue. Starting from day 30, practically no deviation from the normal state of tissues were registered at the site of injection.

Adipose Tissue↗
PubMed1989

Development of local morphological changes after intradermal inoculation of Q-fever chemovaccine.

Development of morphological changes was studied in the site of intradermal inoculation of Q-fever chemovaccine. The chemovaccine was obtained by trichloroacetic acid extraction from Coxiella burnetii, strain Nine mile, phase I cells. The effect of two vaccine doses (0.2 mg and 1.0 mg) was compared in two groups of guinea pigs (each consisting of 21 animals). After inoculation of 1.0 mg vaccine abscesses formed in the dermis and in subcutaneous tissue along with dystrophic changes of skeletal muscles. Reparation of these lesions progressed sufficiently slowly and was not completed before 60 days after vaccine inoculation. The regeneration of skeletal muscles was of budding type. After inoculation of 0.2 mg of chemovaccine minimal lesions occurred in the subcutaneous tissue only. However, already within 48 hr this vaccine dose evoked a strong reparation response. Interesting was the finding of Kurloff cells in the haemorrhagic foci. The results suggest that the low-reactogenic chemovaccine dose of 0.2 mg might be sufficiently immunogenic after subcutaneous administration.

Abscess↗
PubMed1987

Megakaryocytes in rabbit pulmonary blood vessels.

Semiserial sections of lung capillaries of seven rabbits were examined for megakaryocytes. Triads of serial sections of each lobe were examined, and megakaryocyte counts per cm2 were determined. Median megakaryocyte count was determined for each lobe. The lobal values were used to calculate the was determined for each lobe. The lobal values were used to calculate the median cell-counts for each experimental animal. Values of 0.16-0.64 megakaryocytes per cm2 were established as "normal".

Animals↗
PubMed1983

[Pneumoblastoma].

A case of a 55-year old woman with pulmonary blastoma is described. It represents one of the rare pulmonary tumours consisting of nature glandular formations surrounded by mesenchymal structures. Pathogenetic opinions about the lesion are summarized.

Female↗
PubMed1983

[Chronic progressive radiation myelopathy].

Radiation dose absorbed by spinal tissue in 4 cases of chronic progressive myelopathy was analysed so that the criteria could be established for choosing cases in which myelopathy was to be presumed. Nevertheless, neither regressive nor vascular lesion was found in 10 autopsies fitting the criteria. The fact was explained by individual variability or other unknown factors.

Adolescent↗
PubMed1982

[Marinesco bodies in the human mesencephalon].

Substantia nigra in 33 random cases were examined histologically. Quantitative study of the incidence of Marinesco's bodies proved a close relation between the frequency of occurrence and the rising age. Moreover, nosologic units of significantly higher incidence of these inclusions were found than in the cases of other, randomly chosen ones. Their pathogenesis is discussed.

Adult↗