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Biomedical subjects

M Rhein

Publications and source records attributed to M Rhein.

7 recordsLinked to original sources
PubMed1996

A role for CD81 in early T cell development.

Early stages of T cell development are thought to include a series of coordinated interactions between thymocytes and other cells of the thymus. A monoclonal antibody specific for mouse CD81 was identified that blocked the appearance of alpha beta but not gamma delta T cells in fetal organ cultures initiated with day 14.5 thymus lobes. In reaggregation cultures with CD81-transfected fibroblasts, CD4-CD8- thymocytes differentiated into CD4+CD8+ T cells. Thus, interactions between immature thymocytes and stromal cells expressing CD81 are required and may be sufficient to induce early events associated with T cell development.

Amino Acid Sequence↗
PubMed1979

Groups for bereaved parents-how they can help.

The authors wished to establish an organized approach for helping parents of patients who had died. Over a 14-month period, 81 people participated in a series of groups. A closed-group, eight-meeting format was used, under professional leadership. Main topics covered in discussion were: problems and feelings associated with the death of the child; problems of coping with everyday life; and philosophical issues. Conclusions emphasize the need for professional leadership and screening of potential members. The groups were found to be an effective way to help normal people with normal grief. Participants saw their experience as extremely valuable, and as something which could not be gained through conventional therapy.

Adaptation, Psychological↗